Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 2/20 | 0.40 |
| ▸ | CDK9 | P50750 | 1/20 | 0.40 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NSD2 | O96028 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.38 |
| ▸ | CASP1 | P29466 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 1/20 | 0.38 |
| ▸ | CASP7 | P55210 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.38 |
| ▸ | GABRA1 | P14867 | 2/20 | 0.37 |
| ▸ | GABRG2 | P18507 | 2/20 | 0.37 |
| ▸ | GABRB3 | P28472 | 2/20 | 0.37 |
| ▸ | GABRA5 | P31644 | 2/20 | 0.37 |
| ▸ | GABRA3 | P34903 | 2/20 | 0.37 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17099818 | 0.87 | KDM4E (0.44) | CYP11B1CYP11B2KDM4ENSD2LMNA | |
| SCHEMBL29662934 | 0.87 | KDM4E (0.44) | CYP11B1CYP11B2KDM4ENSD2LMNA | |
| SCHEMBL17120698 | 0.81 | CHEK1 (0.48) | CYP11B1CYP11B2KDM4ENSD2LMNA | |
| SCHEMBL17120693 | 0.77 | CNR2 (0.46) | PIM1CDK9CYP11B1CYP11B2CHEK1 | |
| SCHEMBL17099871 | 0.77 | KDM4E (0.47) | CYP11B1CYP11B2KDM4ENSD2LMNA | |
| SCHEMBL17120694 | 0.76 | KDM4E (0.61) | KDM4ENSD2LMNAMAPTTSHR | |
| SCHEMBL25615719 | 0.75 | CHEK1 (0.43) | KDM4ENSD2LMNAMAPTTSHR | |
| SCHEMBL21226418 | 0.75 | CYP11B1 (0.38) | CYP11B1CYP11B2KDM4ELMNAMAPT | |
| SCHEMBL21898956 | 0.73 | CHEK1 (0.45) | KDM4ELMNAMAPTHTTSMN1; SMN2 | |
| SCHEMBL17120696 | 0.70 | RPS6KA3 (0.55) | CHEK1TBK1RPS6KA3RPS6KA2RPS6KA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021055639-A1 | METHODS OF DETECTING NEUROLOGICAL DISORDERS VIA BINDING TO PHOSPHORYLATED TAU PROTEIN | SARRAF STELLA (US) | 2021-03-25 | — | — | WO | disclosed |