Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.44 |
| ▸ | NSD2 | O96028 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.44 |
| ▸ | TSHR | P16473 | 1/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | HTT | P42858 | 1/20 | 0.44 |
| ▸ | CASP7 | P55210 | 1/20 | 0.44 |
| ▸ | CASP6 | P55212 | 1/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.44 |
| ▸ | TBK1 | Q9UHD2 | 5/20 | 0.42 |
| ▸ | CYP11B2 | P19099 | 3/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 3/20 | 0.41 |
| ▸ | TERT | O14746 | 2/20 | 0.40 |
| ▸ | ABL1 | P00519 | 1/20 | 0.40 |
| ▸ | CSNK1D | P48730 | 2/20 | 0.39 |
| ▸ | MAPK11 | Q15759 | 2/20 | 0.39 |
| ▸ | MAPK14 | Q16539 | 2/20 | 0.39 |
| ▸ | ROCK2 | O75116 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17099818 | 1.00 | KDM4E (0.44) | KDM4ENSD2LMNAMAPTTSHR | |
| SCHEMBL17120698 | 0.88 | CHEK1 (0.48) | KDM4ENSD2LMNAMAPTTSHR | |
| SCHEMBL17120694 | 0.88 | KDM4E (0.61) | KDM4ENSD2LMNAMAPTTSHR | |
| SCHEMBL17120693 | 0.87 | CNR2 (0.46) | TBK1CYP11B2CYP11B1CNR2ROCK2 | |
| SCHEMBL23135012 | 0.87 | PIM1 (0.40) | KDM4ENSD2LMNAMAPTTSHR | |
| SCHEMBL17099871 | 0.84 | KDM4E (0.47) | KDM4ENSD2LMNAMAPTTSHR | |
| SCHEMBL17120706 | 0.82 | KDM4E (0.48) | KDM4ENSD2LMNAMAPTTSHR | |
| SCHEMBL25615719 | 0.77 | CHEK1 (0.43) | KDM4ENSD2LMNAMAPTTSHR | |
| SCHEMBL17120925 | 0.76 | KDM4E (0.41) | KDM4ENSD2LMNAMAPTTSHR | |
| SCHEMBL30421146 | 0.76 | KDM4E (0.41) | KDM4ENSD2LMNAMAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119985995-A | Compositions and methods for detecting traumatic brain injury | 阿米达斯公司 | 2025-05-13 | — | — | CN | disclosed |
| CN-112424606-B9 | Compositions and methods for detecting traumatic brain injury | 阿米达斯公司 | 2025-03-07 | — | — | CN | disclosed |
| CN-112424606-B | Compositions and methods for detecting traumatic brain injury | 阿米达斯公司 | 2025-01-14 | — | — | CN | disclosed |
| CN-110483335-B | Amyloid targeting agents and methods of use thereof | 阿米达斯公司 | 2023-08-11 | — | — | CN | disclosed |
| EP-4031879-A1 | METHODS OF DETECTING NEUROLOGICAL DISORDERS VIA BINDING TO PHOSPHORYLATED TAU PROTEIN | Amydis, Inc. (US) | 2022-07-27 | — | — | EP | disclosed |
| CN-114729945-A | Method for detecting neurological diseases by binding to phosphorylated TAU protein | 阿米达斯公司 | 2022-07-08 | — | — | CN | disclosed |