SCHEMBL23135752

SCHEMBL23135752

Cc1cccc(C(O)c2cc(C(=O)c3ccccc3)c(O)c(C)c2O)c1

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL2 P10415 2/20 0.49
MCL1 Q07820 2/20 0.49
POLB P06746 2/20 0.45
CNR2 P34972 2/20 0.41
CNR1 P21554 1/20 0.41
GABRA1 P14867 1/20 0.40
GABRB1 P18505 1/20 0.40
NPSR1 Q6W5P4 2/20 0.39
SMN1; SMN2 Q16637 4/20 0.39
ALDH1A1 P00352 3/20 0.39
MAPT P10636 2/20 0.39
PTGS1 P23219 2/20 0.39
CXCR1 P25024 2/20 0.39
CXCR2 P25025 2/20 0.39
PTGS2 P35354 2/20 0.39
HPGD P15428 2/20 0.39
RECQL P46063 1/20 0.39
ACP3 P15309 1/20 0.39
KDM4E B2RXH2 1/20 0.39
LMNA P02545 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23135202 0.94 POLB (0.46) BCL2MCL1POLBCNR2NPSR1
SCHEMBL23134830 0.80 POLB (0.64) BCL2MCL1POLBCNR2CNR1
SCHEMBL3140205 0.76 BCL2 (0.57) BCL2MCL1POLBGABRA1GABRB1
SCHEMBL3132232 0.75 POLB (0.60) POLBCNR2CNR1NPSR1SMN1; SMN2
SCHEMBL3089697 0.72 BCL2 (0.49) BCL2MCL1GABRA1GABRB1SMN1; SMN2
SCHEMBL23134829 0.72 POLB (0.47) BCL2MCL1POLBCNR2CNR1
SCHEMBL2865160 0.72 BCL2 (0.53) BCL2MCL1POLBGABRA1GABRB1
SCHEMBL5712155 0.70 BCL2 (0.57) BCL2MCL1POLBGABRA1GABRB1
SCHEMBL477409 0.69 ACP3 (0.55) NPSR1SMN1; SMN2ACP3LMNAHTT
SCHEMBL30502803 0.69 ACP3 (0.55) NPSR1SMN1; SMN2ACP3LMNAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11370897-B2 Curable composition comprising UV stabilizer MOMENTIVE PERFORMANCE MATERIALS INC. (US) 2022-06-28 US disclosed
US-20210087355-A1 CURABLE COMPOSITION COMPRISING UV STABILIZER MOMENTIVE PERFORMANCE MATERIALS INC. 2021-03-25 US disclosed