SCHEMBL2865160

SCHEMBL2865160

Cc1cc(C(=O)c2ccccc2)c(O)c(C)c1O

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
BCL2 P10415 1/20 0.53
MCL1 Q07820 1/20 0.53
MEN1 O00255 2/20 0.47
GAA P10253 2/20 0.47
KMT2A Q03164 2/20 0.47
USP2 O75604 1/20 0.47
KEAP1 Q14145 1/20 0.47
NFE2L2 Q16236 1/20 0.47
MAPT P10636 3/20 0.46
MAPK1 P28482 3/20 0.46
KDM4E B2RXH2 2/20 0.46
HSD17B10 Q99714 2/20 0.46
ALOX15 P16050 1/20 0.46
AKR1C3 P42330 2/20 0.46
TDP1 Q9NUW8 2/20 0.45
PSMD14 O00487 1/20 0.45
HSP90AA1 P07900 1/20 0.45
MMP2 P08253 1/20 0.45
THRB P10828 1/20 0.45
NPSR1 Q6W5P4 1/20 0.45

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3140205 0.91 BCL2 (0.57) BCL2MCL1MEN1GAAKMT2A
SCHEMBL8680650 0.87 BCL2 (0.68) BCL2MCL1MEN1GAAKMT2A
SCHEMBL27639385 0.86 BCL2 (0.53) BCL2MCL1MEN1GAAKMT2A
SCHEMBL15483655 0.82 ALDH1A1 (0.40) MEN1GAAKMT2AUSP2MAPT
SCHEMBL2853804 0.82 BCL2 (0.57) BCL2MCL1MEN1GAAKMT2A
SCHEMBL5712263 0.82 GABRA1 (0.53) BCL2MCL1MEN1GAAKMT2A
SCHEMBL2861855 0.82 LMNA (0.53) BCL2MCL1MEN1GAAKMT2A
SCHEMBL23134830 0.81 POLB (0.64) BCL2MCL1MEN1KMT2ATDP1
SCHEMBL4400929 0.81 AKR1C3 (0.57) MEN1GAAKMT2AUSP2KEAP1
SCHEMBL9172083 0.80 MAPT (0.56) BCL2MCL1MEN1GAAKMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106661365-B Fluoropolymer composition comprising at least one oligomer 3M创新有限公司 2019-03-01 CN disclosed
CN-106661400-B Pressure sensitive adhesive compositions comprising ultraviolet light absorbing oligomers 3M创新有限公司 2018-11-13 CN disclosed
CN-105462238-B It is a kind of for extrusion type backboard of photovoltaic cell and preparation method thereof 苏州度辰新材料有限公司 2018-07-03 CN disclosed
CN-106661400-A Pressure sensitive adhesive compositions comprising ultraviolet light absorbing oligomers 3M创新有限公司 2017-05-10 CN disclosed
CN-106661365-A Fluoropolymer composition comprising at least one oligomer 3M创新有限公司 2017-05-10 CN disclosed
US-7713449-B2 Polymer electrolytic material, polymer electrolytic part, membrane electrode assembly, and polymer electrolyte fuel cell TORAY INDUSTRIES, INC. (JP) 2010-05-11 US disclosed
US-20060180796-A1 Polymer electrolyte material, polymer electrolyte part, membrane electrode composite and polymer electrolyte type fuel cell TORAY INDUSTRIES, INC. (JP) 2006-08-17 US disclosed
EP-1619735-A1 POLYMER ELECTROLYTE MATERIAL, POLYMER ELECTROLYTE PART, MEMBRANE ELECTRODE COMPOSITE AND POLYMER ELECTROLYTE TYPE FUEL CELL TORAY INDUSTRIES, INC. (JP) 2006-01-25 EP disclosed