Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23138574 | 1.00 | DPP4 (0.33) | DPP4 | |
| SCHEMBL18390617 | 0.80 | HTR2A (0.42) | DPP4 | |
| SCHEMBL24703359 | 0.78 | DPP4 (0.32) | DPP4 | |
| SCHEMBL24703358 | 0.74 | DPP4 (0.34) | DPP4 | |
| SCHEMBL21739492 | 0.74 | DPP4 (0.32) | DPP4 | |
| SCHEMBL26450622 | 0.74 | DPP4 (0.34) | DPP4 | |
| SCHEMBL24801729 | 0.74 | DPP4 (0.37) | DPP4 | |
| SCHEMBL21739320 | 0.74 | DPP4 (0.34) | DPP4 | |
| SCHEMBL24629551 | 0.74 | HTR2A (0.37) | DPP4 | |
| SCHEMBL761295 | 0.74 | NOS1 (0.42) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021055744-A1 | 4-SUBSTITUTED INDOLE AND INDAZOLE SULFONAMIDO DERIVATIVES AS PARG INHIBITORS | IDEAYA BIOSCIENCES, INC. (US) | 2021-03-25 | — | — | WO | disclosed |