Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LTA4H | P09960 | 2/20 | 0.34 |
| ▸ | PDE4B | Q07343 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 1/20 | 0.33 |
| ▸ | EIF2AK4 | Q9P2K8 | 1/20 | 0.33 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16853906 | 1.00 | LTA4H (0.34) | LTA4HPDE4BDPP4EIF2AK4NOTUM | |
| SCHEMBL21103552 | 0.81 | EIF2AK4 (0.35) | EIF2AK4 | |
| SCHEMBL18590395 | 0.77 | LTA4H (0.36) | LTA4HPDE4BDPP4EIF2AK4NOTUM | |
| SCHEMBL19370311 | 0.77 | HTR2A (0.41) | LTA4HPDE4BDPP4EIF2AK4NOTUM | |
| SCHEMBL18590394 | 0.77 | LTA4H (0.36) | LTA4HPDE4BDPP4EIF2AK4NOTUM | |
| SCHEMBL799513 | 0.77 | HTR2A (0.41) | LTA4HPDE4BDPP4EIF2AK4NOTUM | |
| SCHEMBL19370310 | 0.77 | HTR2A (0.41) | LTA4HPDE4BDPP4EIF2AK4NOTUM | |
| SCHEMBL13486398 | 0.77 | PDE4B (0.34) | LTA4HPDE4BDPP4EIF2AK4 | |
| SCHEMBL18123324 | 0.74 | NOTUM (0.34) | NOTUM | |
| SCHEMBL24802748 | 0.74 | LTA4H (0.42) | LTA4HPDE4BDPP4EIF2AK4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021055744-A1 | 4-SUBSTITUTED INDOLE AND INDAZOLE SULFONAMIDO DERIVATIVES AS PARG INHIBITORS | IDEAYA BIOSCIENCES, INC. (US) | 2021-03-25 | — | — | WO | disclosed |