SCHEMBL23139614

SCHEMBL23139614

CC(C)(C)c1nc(Nc2ccc(Cl)cc2)nc(Nc2ccc3[nH]c(=O)[nH]c3c2)n1

nearest known ligand 0.47

Predicted protein targets (top 19)

geneUniProtsupporting neighboursconfidence
▸ GAA P10253 3/20 0.47
▸ MAPT P10636 2/20 0.47
▸ AURKA O14965 1/20 0.46
▸ AURKB Q96GD4 1/20 0.46
▸ TP53 P04637 1/20 0.43
▸ BCL6 P41182 4/20 0.41
▸ BCOR Q6W2J9 4/20 0.41
▸ THRB P10828 1/20 0.41
▸ ALDH1A1 P00352 2/20 0.40
▸ MEN1 O00255 3/20 0.40
▸ KMT2A Q03164 3/20 0.40
▸ JAK1 P23458 1/20 0.39
▸ JAK3 P52333 1/20 0.39
▸ POLB P06746 2/20 0.39
▸ TSHR P16473 1/20 0.39
▸ CASP1 P29466 1/20 0.39
▸ HBB P68871 1/20 0.39
▸ KDM4E B2RXH2 1/20 0.39
▸ SMN1; SMN2 Q16637 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL23139609 0.92 AURKA (0.46) GAAMAPTAURKAAURKBTP53
SCHEMBL23139623 0.84 KDM4E (0.42) GAAMAPTAURKAAURKBBCL6
SCHEMBL23666320 0.80 RAB9A (0.44) MAPTAURKAAURKBALDH1A1MEN1
SCHEMBL23139617 0.80 GRM4 (0.47) MAPTAURKAAURKBALDH1A1MEN1
SCHEMBL23139630 0.78 AURKA (0.43) GAAMAPTAURKAAURKBBCL6
SCHEMBL23139618 0.77 CA1 (0.43) GAAMAPTAURKAAURKBBCL6
SCHEMBL21927159 0.76 AURKA (0.47) GAAMAPTAURKAAURKBBCL6
SCHEMBL23666322 0.75 POLB (0.35) GAAMAPTAURKAAURKBTP53
SCHEMBL15501260 0.74 AURKA (0.51) GAAMAPTAURKAAURKBTP53
SCHEMBL23786206 0.74 MAPT (0.48) GAAMAPTAURKAAURKBTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12019371-B2 Photosensitive composition, film, color filter, solid-state imaging element, and image display device FUJIFILM CORPORATION (JP) 2024-06-25 — — US disclosed
US-20210223436-A1 STRUCTURAL BODY, SOLID-STATE IMAGING ELEMENT, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2021-07-22 — — US disclosed
US-20210088902-A1 PHOTOSENSITIVE COMPOSITION, FILM, COLOR FILTER, SOLID-STATE IMAGING ELEMENT, AND IMAGE DISPLAY DEVICE FUJIFILM CORPORATION (JP) 2021-03-25 — — US disclosed
Send feedback