Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | UGCG | Q16739 | 2/20 | 0.42 |
| ▸ | SCN9A | Q15858 | 3/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.37 |
| ▸ | HPGD | P15428 | 3/20 | 0.37 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.37 |
| ▸ | ADRA1D | P25100 | 7/20 | 0.37 |
| ▸ | ADRA1A | P35348 | 7/20 | 0.37 |
| ▸ | ADRA1B | P35368 | 7/20 | 0.37 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | CASP1 | P29466 | 1/20 | 0.34 |
| ▸ | CASP7 | P55210 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22729782 | 0.91 | UGCG (0.43) | UGCGSCN9AKDM4EHPGDHSD17B10 | |
| SCHEMBL22729663 | 0.89 | KDM4E (0.45) | UGCGKDM4EHPGDHSD17B10ALDH1A1 | |
| SCHEMBL22729828 | 0.85 | ADRA1A (0.38) | UGCGSCN9AADRA1DADRA1AADRA1B | |
| SCHEMBL22729643 | 0.83 | UGCG (0.51) | UGCGSCN9AKDM4ELMNAMAPT | |
| SCHEMBL29839326 | 0.83 | UGCG (0.51) | UGCGSCN9AKDM4ELMNAMAPT | |
| SCHEMBL29839299 | 0.82 | UGCG (0.67) | UGCGSCN9AKDM4EHPGDHSD17B10 | |
| SCHEMBL22729397 | 0.82 | UGCG (0.67) | UGCGSCN9AKDM4EHPGDHSD17B10 | |
| SCHEMBL22729530 | 0.81 | UGCG (0.48) | UGCGSCN9AMAPK1MAPT | |
| SCHEMBL22729804 | 0.81 | UGCG (0.48) | UGCGSCN9AMAPT | |
| SCHEMBL29839298 | 0.81 | UGCG (0.48) | UGCGSCN9AMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20210087186-A1 | HETEROCYCLIC COMPOUND | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2021-03-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210087186-A1 | HETEROCYCLIC COMPOUND | GBA1, GBA2, GALC | UGCG 8/4885SCN9A 2915/4885KDM4E 1315/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.