⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23145913 | 1.00 | — | — | |
| SCHEMBL23145603 | 1.00 | — | — | |
| SCHEMBL23145515 | 0.85 | — | — | |
| SCHEMBL23146305 | 0.85 | — | — | |
| SCHEMBL23145516 | 0.85 | — | — | |
| SCHEMBL21798024 | 0.67 | — | — | |
| SCHEMBL21407988 | 0.65 | — | — | |
| SCHEMBL21407989 | 0.65 | — | — | |
| SCHEMBL21798054 | 0.65 | APLNR (0.37) | — | |
| SCHEMBL23145799 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12338220-B2 | Antiviral pyrazolopiridinone compounds | GILEAD SCIENCES, INC. (US) | 2025-06-24 | — | — | US | disclosed |
| US-20230365511-A1 | Antiviral Pyrazolopiridinone Compounds | NOVARTIS AG (CH) | 2023-11-16 | — | — | US | disclosed |
| US-20230365511-A1 | Antiviral Pyrazolopiridinone Compounds | NOVARTIS AG (CH) | 2023-11-16 | — | — | US | disclosed |
| US-11667613-B2 | Antiviral pyrazolopyridinone compounds | NOVARTIS AG (CH) | 2023-06-06 | — | — | US | disclosed |
| EP-4034537-A1 | ANTIVIRAL PYRAZOLOPYRIDINONE COMPOUNDS | Novartis AG (CH) | 2022-08-03 | — | — | EP | disclosed |
| CN-114667285-A | Antiviral pyrazolopyridinone compounds | 诺华股份有限公司 | 2022-06-24 | — | — | CN | disclosed |
| US-20210130302-A1 | Antiviral Pyrazolopyridinone Compounds | NOVARTIS INSTITUTES FOR BIOMEDICAL RESEARCH INC | 2021-05-06 | — | — | US | disclosed |
| WO-2021061898-A1 | ANTIVIRAL PYRAZOLOPYRIDINONE COMPOUNDS | NOVARTIS AG (CH) | 2021-04-01 | — | — | WO | disclosed |