Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.61 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.61 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.61 |
| ▸ | LMNA | P02545 | 2/20 | 0.61 |
| ▸ | TP53 | P04637 | 1/20 | 0.61 |
| ▸ | HPGD | P15428 | 1/20 | 0.61 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.61 |
| ▸ | ESR1 | P03372 | 3/20 | 0.58 |
| ▸ | ESR2 | Q92731 | 3/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.52 |
| ▸ | IDO1 | P14902 | 2/20 | 0.41 |
| ▸ | TDO2 | P48775 | 2/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.35 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.35 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.35 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.35 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.35 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.35 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bromide SCHEMBL11313586 | 0.95 | TSHR (0.56) | TSHRMAPK1TDP1LMNATP53 | |
| SCHEMBL23149866 | 0.91 | TSHR (0.78) | TSHRMAPK1TDP1LMNATP53 | |
| Alcohol SCHEMBL4003601 | 0.89 | ESR1 (0.54) | TSHRMAPK1TDP1LMNATP53 | |
| Chlorophenothane SCHEMBL7181 | 0.76 | TSHR (1.00) | TSHRMAPK1TDP1LMNATP53 | |
| Chlorophenothane SCHEMBL2065589 | 0.76 | TSHR (1.00) | TSHRMAPK1TDP1LMNATP53 | |
| SCHEMBL22326114 | 0.76 | ESR1 (0.64) | TSHRMAPK1TDP1LMNATP53 | |
| SCHEMBL23149894 | 0.75 | AOC3 (0.38) | TSHRMAPK1TDP1LMNATP53 | |
| SCHEMBL23149874 | 0.75 | AOC3 (0.38) | TSHRMAPK1TDP1LMNATP53 | |
| SCHEMBL23149895 | 0.75 | AOC3 (0.38) | TSHRMAPK1TDP1LMNATP53 | |
| SCHEMBL23149873 | 0.75 | ESR1 (0.39) | TSHRMAPK1TDP1LMNATP53 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1151 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240209329-A1 | PROGRAMMABLE CAS9-RECOMBINASE FUSION PROTEINS AND USES THEREOF | PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) | 2024-06-27 | — | — | US | claimed |
| CN-118202041-A | Background specific adenine base editor and application thereof | 布罗德研究所股份有限公司 | 2024-06-14 | — | — | CN | claimed |
| US-11969239-B2 | Tumor tissue characterization using multi-parametric magnetic resonance imaging | Siemens Healthineers Ag (DE) | 2024-04-30 | — | — | US | claimed |
| CN-117749637-A | Network damage combined simulation implementation method and system | 山东省计算中心（国家超级计算济南中心） | 2024-03-22 | — | — | CN | claimed |
| US-20240035039-A1 | PLANT REGULATORY ELEMENTS AND USES THEREOF FOR AUTOEXCISION | MONSANTO TECHNOLOGY LLC (US) | 2024-02-01 | — | — | US | claimed |
| WO-2024017331-A1 | ANTI-ADRENOMEDULIN NON-NEUTRALIZING ANTIBODY, METHOD FOR PREPARING SAME, AND USE THEREOF | 上海济煜医药科技有限公司 | 2024-01-25 | — | — | WO | claimed |
| WO-2023201186-A1 | PLANT REGULATORY ELEMENTS AND USES THEREOF FOR AUTOEXCISION | MONSANTO TECHNOLOGY LLC (US) | 2023-10-19 | — | — | WO | claimed |
| EP-3703007-B1 | TUMOR TISSUE CHARACTERIZATION USING MULTI-PARAMETRIC MAGNETIC RESONANCE IMAGING | SIEMENS HEALTHCARE GMBH (DE) | 2023-10-18 | — | — | EP | claimed |
| EP-4232587-A1 | PLANT REGULATORY ELEMENTS AND USES THEREOF FOR AUTOEXCISION | Monsanto Technology LLC (US) | 2023-08-30 | — | — | EP | claimed |
| CN-116646944-A | Island micro-grid low-frequency load shedding method considering inertia distribution | 南京理工大学 | 2023-08-25 | — | — | CN | claimed |
| US-20040137624-A1 | Methods of site-directed transformation | MONSANTO TECHNOLOGY, L.L.C. | 2004-07-15 | — | — | US | claimed |
| US-6723896-B1 | Inducible site-specific recombination for the activation and removal of transgenes in transgenic plants | THE ROCKEFELLER UNIVERSITY | 2004-04-20 | — | — | US | claimed |
| US-20030148263-A1 | Methods and compositions using genetic package display | SELECTIVE GENETICS, INC. (US) | 2003-08-07 | — | — | US | claimed |
| CN-1423701-A | Inducible site-specific recombination for the activation and removal of transgenes in transgenic plants | UNIV ROCKEFELLER (US) | 2003-06-11 | — | — | CN | claimed |
| US-20030100077-A1 | In vitro method to create circular molecules for use in transformation | MONSANTO TECHNOLOGY LLC | 2003-05-29 | — | — | US | claimed |
| EP-1232275-A2 | INDUCIBLE SITE-SPECIFIC RECOMBINATION FOR THE ACTIVATION AND REMOVAL OF TRANSGENES IN TRANSGENIC PLANTS | THE ROCKEFELLER UNIVERSITY (US) | 2002-08-21 | — | — | EP | claimed |
| US-6392412-B1 | Method of correcting higher order field inhomogeneities in a magnetic resonance apparatus | BRUKER MEDICAL GMBH (DE) | 2002-05-21 | — | — | US | claimed |
| WO-2001040492-A2 | INDUCIBLE SITE-SPECIFIC RECOMBINATION FOR THE ACTIVATION AND REMOVAL OF TRANSGENES IN TRANSGENIC PLANTS | THE ROCKEFELLER UNIVERSITY (US) | 2001-06-07 | — | — | WO | claimed |
| CN-1292416-A | Molcular method for removing specific tissue of transgenic plant or target gene in organ by utilizing location recombination system | LIN ZHONGPING (CN) | 2001-04-25 | — | — | CN | claimed |
| EP-0416370-B1 | Method and device for detecting and indentifying sensor errors | BODENSEEWERK GERAETETECH (DE) | 1995-11-22 | — | — | EP | claimed |