Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 7/20 | 0.53 |
| ▸ | MMEL1 | Q495T6 | 3/20 | 0.53 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.49 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.49 |
| ▸ | CTSG | P08311 | 1/20 | 0.46 |
| ▸ | CMA1 | P23946 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.46 |
| ▸ | PTPRB | P23467 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | TP53 | P04637 | 1/20 | 0.44 |
| ▸ | GAA | P10253 | 1/20 | 0.44 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2314748 | 1.00 | MME (0.53) | MMEMMEL1ITGB1ITGA4CTSG | |
| SCHEMBL2319273 | 0.90 | MME (0.48) | MMEMMEL1ITGB1ITGA4CTSG | |
| SCHEMBL2319282 | 0.90 | MME (0.48) | MMEMMEL1ITGB1ITGA4CTSG | |
| SCHEMBL2319566 | 0.88 | MME (0.50) | MMEMMEL1ITGB1ITGA4CTSG | |
| SCHEMBL2319559 | 0.88 | MME (0.50) | MMEMMEL1ITGB1ITGA4CTSG | |
| SCHEMBL2313448 | 0.87 | MME (0.50) | MMEMMEL1ITGB1ITGA4CTSG | |
| SCHEMBL2313433 | 0.87 | MME (0.50) | MMEMMEL1ITGB1ITGA4CTSG | |
| SCHEMBL2317015 | 0.87 | MME (0.51) | MMEMMEL1ITGB1ITGA4CTSG | |
| SCHEMBL2317022 | 0.87 | MME (0.51) | MMEMMEL1ITGB1ITGA4CTSG | |
| SCHEMBL2320793 | 0.82 | PIN1 (0.54) | MMEMMEL1ITGB1ITGA4CTSG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092284-A1 | NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS | EUROSCREEN S.A. (BE) | 2011-08-04 | — | — | WO | claimed |