Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 4/20 | 0.61 |
| ▸ | CNR2 | P34972 | 4/20 | 0.60 |
| ▸ | LTA4H | P09960 | 1/20 | 0.53 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.53 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.50 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.47 |
| ▸ | CTSG | P08311 | 1/20 | 0.46 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.46 |
| ▸ | UTS2R | Q9UKP6 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.46 |
| ▸ | PLAAT3 | P53816 | 1/20 | 0.45 |
| ▸ | PLAAT5 | Q96KN8 | 1/20 | 0.45 |
| ▸ | PLAAT2 | Q9NWW9 | 1/20 | 0.45 |
| ▸ | PLAAT4 | Q9UL19 | 1/20 | 0.45 |
| ▸ | MME | P08473 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2314749 | 1.00 | FFAR2 (0.61) | FFAR2CNR2LTA4HEPHX2HDAC1 | |
| SCHEMBL2320615 | 0.88 | CNR2 (0.67) | CNR2HDAC8ALDH1A1CTSGCTRB1 | |
| SCHEMBL2320622 | 0.88 | CNR2 (0.67) | CNR2HDAC8ALDH1A1CTSGCTRB1 | |
| SCHEMBL2364853 | 0.88 | FFAR2 (0.77) | FFAR2CNR2MME | |
| SCHEMBL2364855 | 0.88 | FFAR2 (0.77) | FFAR2CNR2MME | |
| SCHEMBL2312496 | 0.84 | CNR2 (0.57) | CNR2EPHX2ALDH1A1CTSGCTRB1 | |
| SCHEMBL2316069 | 0.84 | CNR2 (0.57) | FFAR2CNR2LTA4HEPHX2ALDH1A1 | |
| SCHEMBL2316063 | 0.84 | CNR2 (0.57) | FFAR2CNR2LTA4HEPHX2ALDH1A1 | |
| SCHEMBL2312501 | 0.84 | CNR2 (0.57) | CNR2EPHX2ALDH1A1CTSGCTRB1 | |
| SCHEMBL2316180 | 0.84 | CNR2 (0.57) | CNR2ALDH1A1CTSGCTRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092284-A1 | NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS | EUROSCREEN S.A. (BE) | 2011-08-04 | — | — | WO | claimed |