Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 2/20 | 0.51 |
| ▸ | POLB | P06746 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.45 |
| ▸ | CTSG | P08311 | 1/20 | 0.44 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MME | P08473 | 2/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2314825 | 1.00 | CNR2 (0.51) | CNR2POLBMAPTSIGMAR1CTSG | |
| SCHEMBL2320622 | 0.87 | CNR2 (0.67) | CNR2POLBCTSGCTRB1ALDH1A1 | |
| SCHEMBL2320615 | 0.87 | CNR2 (0.67) | CNR2POLBCTSGCTRB1ALDH1A1 | |
| SCHEMBL2316553 | 0.81 | POLB (0.71) | CNR2POLBSIGMAR1TDP1L3MBTL1 | |
| SCHEMBL2316546 | 0.81 | POLB (0.71) | CNR2POLBSIGMAR1TDP1L3MBTL1 | |
| SCHEMBL2316180 | 0.80 | CNR2 (0.57) | CNR2POLBMAPTCTSGCTRB1 | |
| SCHEMBL2316172 | 0.80 | CNR2 (0.57) | CNR2POLBMAPTCTSGCTRB1 | |
| SCHEMBL2312496 | 0.80 | CNR2 (0.57) | CNR2POLBMAPTCTSGCTRB1 | |
| SCHEMBL2316069 | 0.80 | CNR2 (0.57) | CNR2CTSGCTRB1ALDH1A1MME | |
| SCHEMBL2316063 | 0.80 | CNR2 (0.57) | CNR2CTSGCTRB1ALDH1A1MME |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092284-A1 | NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS | EUROSCREEN S.A. (BE) | 2011-08-04 | — | — | WO | claimed |
| WO-2011092284-A1 | NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS | EUROSCREEN S.A. (BE) | 2011-08-04 | — | — | WO | disclosed |