Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR2 | P34972 | 3/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.52 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | CTSG | P08311 | 1/20 | 0.46 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.46 |
| ▸ | MMP12 | P39900 | 1/20 | 0.46 |
| ▸ | MMP13 | P45452 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 1/20 | 0.45 |
| ▸ | ECE1 | P42892 | 1/20 | 0.45 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.43 |
| ▸ | PRKACA | P17612 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 2/20 | 0.43 |
| ▸ | MMP3 | P08254 | 1/20 | 0.43 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2316180 | 1.00 | CNR2 (0.57) | CNR2ALDH1A1GAAMAPTPOLB | |
| SCHEMBL2320615 | 0.92 | CNR2 (0.67) | CNR2ALDH1A1GAAPOLBCTSG | |
| SCHEMBL2320622 | 0.92 | CNR2 (0.67) | CNR2ALDH1A1GAAPOLBCTSG | |
| SCHEMBL2316063 | 0.84 | CNR2 (0.57) | CNR2ALDH1A1CTSGCTRB1 | |
| SCHEMBL2312501 | 0.84 | CNR2 (0.57) | CNR2ALDH1A1GAAMAPTPOLB | |
| SCHEMBL2316069 | 0.84 | CNR2 (0.57) | CNR2ALDH1A1CTSGCTRB1 | |
| SCHEMBL2312496 | 0.84 | CNR2 (0.57) | CNR2ALDH1A1GAAMAPTPOLB | |
| SCHEMBL2314754 | 0.84 | FFAR2 (0.61) | CNR2ALDH1A1CTSGCTRB1 | |
| SCHEMBL2314749 | 0.84 | FFAR2 (0.61) | CNR2ALDH1A1CTSGCTRB1 | |
| SCHEMBL2316553 | 0.81 | POLB (0.71) | CNR2ALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092284-A1 | NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS | EUROSCREEN S.A. (BE) | 2011-08-04 | — | — | WO | claimed |
| WO-2011092284-A1 | NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS | EUROSCREEN S.A. (BE) | 2011-08-04 | — | — | WO | disclosed |