Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 3/20 | 0.62 |
| ▸ | MMEL1 | Q495T6 | 9/20 | 0.52 |
| ▸ | MME | P08473 | 4/20 | 0.52 |
| ▸ | POLB | P06746 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ACE | P12821 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2314911 | 1.00 | FFAR2 (0.62) | FFAR2MMEL1MMEPOLBMEN1 | |
| SCHEMBL2313265 | 0.88 | FFAR2 (0.77) | FFAR2MMEL1MMEMEN1ALDH1A1 | |
| SCHEMBL2313273 | 0.88 | FFAR2 (0.77) | FFAR2MMEL1MMEMEN1ALDH1A1 | |
| SCHEMBL2317645 | 0.86 | MME (0.59) | FFAR2MMEL1MMEPOLBHPGD | |
| SCHEMBL2318159 | 0.86 | MME (0.59) | FFAR2MMEL1MMEPOLBHPGD | |
| SCHEMBL2317640 | 0.86 | MME (0.59) | FFAR2MMEL1MMEPOLBHPGD | |
| SCHEMBL2316468 | 0.85 | FFAR2 (0.47) | FFAR2MMEL1MMEPOLB | |
| SCHEMBL2316475 | 0.85 | FFAR2 (0.47) | FFAR2MMEL1MMEPOLB | |
| SCHEMBL2314323 | 0.84 | FFAR2 (0.59) | FFAR2MMEMEN1KMT2ANPC1 | |
| SCHEMBL2314316 | 0.84 | FFAR2 (0.59) | FFAR2MMEMEN1KMT2ANPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092284-A1 | NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS | EUROSCREEN S.A. (BE) | 2011-08-04 | — | — | WO | claimed |