Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.41 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.36 |
| ▸ | TMEM97 | Q5BJF2 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | DAO | P14920 | 1/20 | 0.36 |
| ▸ | NAAA | Q02083 | 1/20 | 0.36 |
| ▸ | ENPP2 | Q13822 | 3/20 | 0.35 |
| ▸ | ATXN2 | Q99700 | 3/20 | 0.35 |
| ▸ | TACR1 | P25103 | 2/20 | 0.34 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.34 |
| ▸ | PRKX | P51817 | 1/20 | 0.34 |
| ▸ | IKBKE | Q14164 | 1/20 | 0.34 |
| ▸ | S1PR5 | Q9H228 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | LTC4S | Q16873 | 1/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.33 |
| ▸ | KDM1A | O60341 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL23149354 | 1.00 | IDO1 (0.41) | IDO1SLC6A4FFAR1P2RY14TMEM97 | |
| Trifluoroacetic Acid SCHEMBL23149348 | 1.00 | IDO1 (0.41) | IDO1SLC6A4FFAR1P2RY14TMEM97 | |
| SCHEMBL23105381 | 0.92 | IDO1 (0.48) | IDO1SLC6A4FFAR1P2RY14TMEM97 | |
| SCHEMBL23171801 | 0.92 | IDO1 (0.48) | IDO1SLC6A4FFAR1P2RY14TMEM97 | |
| SCHEMBL23171806 | 0.92 | IDO1 (0.48) | IDO1SLC6A4FFAR1P2RY14TMEM97 | |
| Trifluoroacetic Acid SCHEMBL21723023 | 0.83 | SLC6A4 (0.44) | IDO1SLC6A4FFAR1SLC6A2SLC6A3 | |
| Trifluoroacetic Acid SCHEMBL23149404 | 0.82 | IDO1 (0.41) | IDO1SLC6A4FFAR1P2RY14TMEM97 | |
| Trifluoroacetic Acid SCHEMBL23149406 | 0.82 | IDO1 (0.41) | IDO1SLC6A4FFAR1P2RY14TMEM97 | |
| Trifluoroacetic Acid SCHEMBL23152297 | 0.80 | IDO1 (0.47) | IDO1SLC6A4FFAR1SLC6A2SLC6A3 | |
| Trifluoroacetic Acid SCHEMBL23091803 | 0.78 | NAAA (0.43) | IDO1SLC6A4FFAR1SLC6A2SLC6A3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-4028401-B1 | 4,4A,5,7,8,8A-HEXAPYRIDO[4,3-B][1,4]OXAZIN-3-ONE COMPOUNDS AS MAGL INHIBITORS | HOFFMANN LA ROCHE (CH) | 2023-11-22 | — | — | EP | disclosed |
| US-20220275005-A1 | HETEROCYCLIC COMPOUNDS | HOFFMANN-LA ROCHE INC. (US) | 2022-09-01 | — | — | US | disclosed |
| US-20210094971-A1 | HETEROCYCLIC COMPOUNDS | HOFFMANN-LA ROCHE INC. (US) | 2021-04-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20210094971-A1 | HETEROCYCLIC COMPOUNDS | CYP1B1, CYP4B1, CYP4X1 | IDO1 1248/4885SLC6A4 4287/4885FFAR1 4200/4885 |
| US-20220275005-A1 | HETEROCYCLIC COMPOUNDS | CYP1B1, CYP4B1, CYP4X1 | IDO1 1248/4885SLC6A4 4287/4885FFAR1 4200/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.