SCHEMBL2314959

SCHEMBL2314959

O=C(O)C[C@@H](Cc1ccc(Cl)cc1)NC(=O)Cc1ccc(Cl)cc1

nearest known ligand 0.71

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MME P08473 7/20 0.71
FFAR2 O15552 2/20 0.61
MMEL1 Q495T6 4/20 0.57
PSMB8 P28062 1/20 0.57
PSMB5 P28074 1/20 0.57
CNR2 P34972 5/20 0.56
KMT2A Q03164 2/20 0.53

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2314965 1.00 MME (0.71) MMEFFAR2MMEL1PSMB8PSMB5
SCHEMBL2313700 0.96 MME (0.66) MMEFFAR2MMEL1PSMB8PSMB5
SCHEMBL2313693 0.96 MME (0.66) MMEFFAR2MMEL1PSMB8PSMB5
SCHEMBL2314065 0.96 MME (0.66) MMEFFAR2MMEL1PSMB8PSMB5
SCHEMBL2317689 0.93 MME (0.63) MMEFFAR2MMEL1PSMB8PSMB5
SCHEMBL2317683 0.93 MME (0.63) MMEFFAR2MMEL1PSMB8PSMB5
SCHEMBL2313244 0.93 MME (0.63) MMEFFAR2MMEL1PSMB8PSMB5
SCHEMBL2313239 0.93 MME (0.63) MMEFFAR2MMEL1PSMB8PSMB5
SCHEMBL2315686 0.91 CNR2 (0.63) MMEFFAR2MMEL1CNR2KMT2A
SCHEMBL2315696 0.91 CNR2 (0.63) MMEFFAR2MMEL1CNR2KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2011092284-A1 NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS EUROSCREEN S.A. (BE) 2011-08-04 WO claimed