Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 7/20 | 0.66 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.64 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.64 |
| ▸ | PSMB5 | P28074 | 2/20 | 0.64 |
| ▸ | CNR2 | P34972 | 3/20 | 0.59 |
| ▸ | MMEL1 | Q495T6 | 2/20 | 0.55 |
| ▸ | MEN1 | O00255 | 1/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2313700 | 1.00 | MME (0.66) | MMEFFAR2PSMB8PSMB5CNR2 | |
| SCHEMBL2314065 | 1.00 | MME (0.66) | MMEFFAR2PSMB8PSMB5CNR2 | |
| SCHEMBL2314965 | 0.96 | MME (0.71) | MMEFFAR2PSMB8PSMB5CNR2 | |
| SCHEMBL2314959 | 0.96 | MME (0.71) | MMEFFAR2PSMB8PSMB5CNR2 | |
| SCHEMBL2315245 | 0.90 | FFAR2 (0.79) | MMEFFAR2PSMB8PSMB5MMEL1 | |
| SCHEMBL2315341 | 0.90 | FFAR2 (0.79) | MMEFFAR2PSMB8PSMB5MMEL1 | |
| SCHEMBL2315240 | 0.90 | FFAR2 (0.79) | MMEFFAR2PSMB8PSMB5MMEL1 | |
| SCHEMBL2313239 | 0.89 | MME (0.63) | MMEFFAR2PSMB8PSMB5CNR2 | |
| SCHEMBL2317683 | 0.89 | MME (0.63) | MMEFFAR2PSMB8PSMB5CNR2 | |
| SCHEMBL2313244 | 0.89 | MME (0.63) | MMEFFAR2PSMB8PSMB5CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092284-A1 | NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS | EUROSCREEN S.A. (BE) | 2011-08-04 | — | — | WO | claimed |
| WO-2011092284-A1 | NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS | EUROSCREEN S.A. (BE) | 2011-08-04 | — | — | WO | disclosed |