Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMYD3 | Q9H7B4 | 19/20 | 0.39 |
| ▸ | F2 | P00734 | 1/20 | 0.33 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.33 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.33 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.33 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20445357 | 1.00 | SMYD3 (0.39) | SMYD3F2PRSS1PRSS2PRSS3 | |
| SCHEMBL7886607 | 0.89 | — | — | |
| SCHEMBL26044995 | 0.88 | SMYD3 (0.30) | SMYD3 | |
| SCHEMBL4269720 | 0.80 | SMYD3 (0.36) | SMYD3F2PRSS1PRSS2PRSS3 | |
| SCHEMBL26181536 | 0.80 | — | — | |
| SCHEMBL24340204 | 0.80 | EPHX2 (0.48) | F2ST14 | |
| SCHEMBL4269726 | 0.80 | SMYD3 (0.36) | SMYD3F2PRSS1PRSS2PRSS3 | |
| SCHEMBL14595306 | 0.80 | EPHX2 (0.48) | F2ST14 | |
| SCHEMBL4103966 | 0.79 | SIGMAR1 (0.43) | — | |
| SCHEMBL26044029 | 0.79 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-10960003-B2 | Pyrazole pyrimidine derivative and uses thereof | BIOTHERYX, INC. (US) | 2021-03-30 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10960003-B2 | Pyrazole pyrimidine derivative and uses thereof | IRAK1, IRAK2, IRAK3 | SMYD3 3792/4885F2 4315/4885PRSS1 771/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.