Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.36 |
| ▸ | EGFR | P00533 | 3/20 | 0.36 |
| ▸ | MAPKAPK2 | P49137 | 2/20 | 0.34 |
| ▸ | IGF1R | P08069 | 4/20 | 0.34 |
| ▸ | INSR | P06213 | 2/20 | 0.33 |
| ▸ | ALK | Q9UM73 | 2/20 | 0.33 |
| ▸ | SCN2A | Q99250 | 1/20 | 0.33 |
| ▸ | SCN10A | Q9Y5Y9 | 1/20 | 0.33 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.33 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.33 |
| ▸ | CDK7 | P50613 | 1/20 | 0.32 |
| ▸ | CDK9 | P50750 | 1/20 | 0.32 |
| ▸ | EGLN1 | Q9GZT9 | 2/20 | 0.32 |
| ▸ | XDH | P47989 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CSF1R | P07333 | 1/20 | 0.32 |
| ▸ | PLAU | P00749 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23154188 | 0.91 | RAF1 (0.38) | MEN1KMT2AEGFRIGF1RINSR | |
| SCHEMBL23153875 | 0.87 | EGFR (0.42) | MEN1KMT2AEGFRIGF1RINSR | |
| SCHEMBL29975976 | 0.87 | EGFR (0.42) | MEN1KMT2AEGFRIGF1RINSR | |
| SCHEMBL23154196 | 0.84 | EGFR (0.38) | MEN1KMT2AEGFRIGF1RINSR | |
| SCHEMBL23153842 | 0.83 | EGFR (0.38) | MEN1KMT2AEGFRIGF1RINSR | |
| SCHEMBL23153748 | 0.82 | EGFR (0.41) | MEN1KMT2AEGFRIGF1RINSR | |
| SCHEMBL23154240 | 0.82 | EGFR (0.38) | MEN1KMT2AEGFRIGF1RINSR | |
| SCHEMBL23154221 | 0.82 | MEN1 (0.39) | MEN1KMT2AEGFRIGF1RINSR | |
| SCHEMBL23154152 | 0.82 | ALK (0.39) | MEN1KMT2AEGFRIGF1RINSR | |
| SCHEMBL24179135 | 0.81 | MEN1 (0.43) | MEN1KMT2AEGFRIGF1RINSR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021057882-A1 | EGFR INHIBITOR, COMPOSITION AND PREPARATION METHOD THEREFOR | 贝达药业股份有限公司 | 2021-04-01 | — | — | WO | disclosed |