Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | QPCTL | Q9NXS2 | 3/20 | 0.49 |
| ▸ | PIK3R1 | P27986 | 2/20 | 0.42 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.42 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.41 |
| ▸ | GFER | P55789 | 1/20 | 0.41 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | CMA1 | P23946 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.37 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.37 |
| ▸ | MET | P08581 | 1/20 | 0.36 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23156292 | 0.87 | QPCTL (0.50) | QPCTLPIK3R1PIK3CAP2RX7GAA | |
| SCHEMBL23156356 | 0.76 | QPCTL (0.54) | QPCTLPIK3R1PIK3CAP2RX7GAA | |
| SCHEMBL23116078 | 0.75 | QPCTL (0.46) | QPCTLP2RX7CYP11B1CYP11B2KDM4E | |
| SCHEMBL20413799 | 0.73 | QPCTL (0.52) | QPCTLP2RX7GAAGFERCYP11B1 | |
| SCHEMBL7512001 | 0.72 | QPCTL (0.58) | QPCTLP2RX7GAAGFERCYP11B1 | |
| SCHEMBL23115720 | 0.71 | QPCTL (0.46) | QPCTLP2RX7CYP11B1CYP11B2KDM4E | |
| SCHEMBL26690111 | 0.70 | QPCTL (0.45) | QPCTLP2RX7GAAGFERCYP11B1 | |
| SCHEMBL14204032 | 0.69 | QPCTL (0.48) | QPCTLP2RX7CYP11B1CYP11B2KDM4E | |
| SCHEMBL17982169 | 0.67 | CYP11B2 (0.52) | QPCTLP2RX7CYP11B1CYP11B2KDM4E | |
| SCHEMBL23115689 | 0.67 | QPCTL (0.49) | QPCTLP2RX7CYP11B1CYP11B2KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021059136-A1 | POLYHETEROCYCLIC MODULATORS OF STING (STIMULATOR OF INTERFERON GENES) | PFIZER INC. (US) | 2021-04-01 | — | — | WO | disclosed |