⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13677425 | 0.82 | — | — | |
| SCHEMBL9203433 | 0.81 | QDPR (0.42) | — | |
| Hydrochloric Acid SCHEMBL10418851 | 0.79 | QDPR (0.41) | — | |
| Hydrochloric Acid SCHEMBL14311881 | 0.79 | QDPR (0.41) | — | |
| SCHEMBL5203140 | 0.78 | CHRM2 (0.65) | — | |
| SCHEMBL12918271 | 0.77 | CHRM3 (0.68) | — | |
| SCHEMBL20334673 | 0.77 | CHRM2 (0.37) | — | |
| SCHEMBL23178984 | 0.77 | CHRM2 (0.37) | — | |
| SCHEMBL23735704 | 0.75 | CHRM2 (0.36) | — | |
| SCHEMBL28303574 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12435087-B2 | Modulators of DCN-1 and methods of use thereof | CELLARITY, INC. (US) | 2025-10-07 | — | — | US | disclosed |
| US-20250163058-A1 | MODULATORS OF DCN-1 AND METHODS OF USE THEREOF | THAMES PHARMA PARTNERS | 2025-05-22 | — | — | US | disclosed |
| WO-2025096981-A1 | MODULATORS OF DCN-1 AND METHODS OF USE THEREOF | CELLARITY, INC. (US) | 2025-05-08 | — | — | WO | disclosed |
| WO-2021057832-A1 | KRAS MUTANT PROTEIN INHIBITOR | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2021-04-01 | — | — | WO | disclosed |