Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GBA2 | Q9HCG7 | 15/20 | 0.38 |
| ▸ | GAA | P10253 | 5/20 | 0.38 |
| ▸ | GBA1 | P04062 | 5/20 | 0.38 |
| ▸ | UGCG | Q16739 | 3/20 | 0.38 |
| ▸ | MGAM | O43451 | 2/20 | 0.38 |
| ▸ | SI | P14410 | 2/20 | 0.38 |
| ▸ | AGL | P35573 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | TLR7 | Q9NYK1 | 1/20 | 0.35 |
| ▸ | KIF11 | P52732 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL16511216 | 1.00 | GBA2 (0.38) | GBA2GAAGBA1UGCGMGAM | |
| SCHEMBL25914962 | 0.93 | GBA2 (0.41) | GBA2GAAGBA1UGCG | |
| SCHEMBL12717919 | 0.89 | ESR1 (0.34) | GAATLR7KIF11 | |
| SCHEMBL8369391 | 0.89 | ESR1 (0.34) | GAATLR7KIF11 | |
| SCHEMBL12716623 | 0.89 | ESR1 (0.34) | GAATLR7KIF11 | |
| SCHEMBL23074745 | 0.82 | GBA1 (0.36) | GBA1KIF11 | |
| SCHEMBL23074743 | 0.82 | GBA1 (0.36) | GBA1KIF11 | |
| SCHEMBL15699287 | 0.82 | GBA1 (0.36) | GBA1KIF11 | |
| SCHEMBL23158261 | 0.81 | KIF11 (0.33) | KIF11 | |
| SCHEMBL19617858 | 0.81 | KIF11 (0.34) | KIF11 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021127404-A1 | TRICYCLIC PYRIDONES AND PYRIMIDONES | ERASCA, INC. (US) | 2021-06-24 | — | — | WO | disclosed |
| WO-2021057832-A1 | KRAS MUTANT PROTEIN INHIBITOR | JACOBIO PHARMACEUTICALS CO., LTD. (CN) | 2021-04-01 | — | — | WO | disclosed |