Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKZF2 | Q9UKS7 | 15/20 | 0.67 |
| ▸ | IKZF1 | Q13422 | 4/20 | 0.51 |
| ▸ | ESR1 | P03372 | 1/20 | 0.49 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22645559 | 0.89 | CRBN (0.58) | IKZF2ESR1CRBN | |
| SCHEMBL22645556 | 0.89 | CRBN (0.58) | IKZF2ESR1CRBN | |
| SCHEMBL29482928 | 0.89 | IKZF2 (0.65) | IKZF2IKZF1 | |
| SCHEMBL24319397 | 0.89 | IKZF2 (0.65) | IKZF2IKZF1 | |
| SCHEMBL22645537 | 0.88 | IKZF2 (0.51) | IKZF2IKZF1ESR1CRBN | |
| SCHEMBL22645533 | 0.88 | IKZF2 (0.51) | IKZF2IKZF1ESR1CRBN | |
| SCHEMBL20765615 | 0.83 | IKZF2 (0.86) | IKZF2IKZF1 | |
| SCHEMBL30369163 | 0.83 | IKZF2 (0.86) | IKZF2IKZF1 | |
| SCHEMBL29597401 | 0.83 | CRBN (0.56) | IKZF2ESR1CRBN | |
| SCHEMBL26578634 | 0.82 | IKZF2 (0.81) | IKZF2IKZF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021061204-A1 | NOVEL SUBSTITUTED QUINOLINE-8-CARBONITRILE DERIVATIVES HAVING ANDROGEN RECEPTOR DEGRADATION ACTIVITY AND USES THEREOF | ACCUTAR BIOTECHNOLOGY INC. (US) | 2021-04-01 | — | — | WO | disclosed |