Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKZF2 | Q9UKS7 | 15/20 | 0.65 |
| ▸ | IKZF1 | Q13422 | 5/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29482928 | 1.00 | IKZF2 (0.65) | IKZF2IKZF1 | |
| SCHEMBL23158456 | 0.89 | IKZF2 (0.67) | IKZF2IKZF1 | |
| SCHEMBL20765615 | 0.85 | IKZF2 (0.86) | IKZF2IKZF1 | |
| SCHEMBL30369163 | 0.85 | IKZF2 (0.86) | IKZF2IKZF1 | |
| SCHEMBL27298672 | 0.84 | IKZF2 (0.78) | IKZF2IKZF1 | |
| SCHEMBL20766794 | 0.84 | IKZF2 (0.80) | IKZF2IKZF1 | |
| SCHEMBL30369169 | 0.84 | IKZF2 (0.80) | IKZF2IKZF1 | |
| SCHEMBL20765795 | 0.84 | IKZF2 (0.80) | IKZF2IKZF1 | |
| SCHEMBL30369457 | 0.84 | IKZF2 (0.80) | IKZF2IKZF1 | |
| SCHEMBL24407622 | 0.83 | IKZF2 (0.87) | IKZF2IKZF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2022047145-A1 | RAPIDLY ACCELERATING FIBROSARCOMA PROTEIN DEGRADING COMPOUNDS AND ASSOCIATED METHODS OF USE | ARVINAS OPERATIONS, INC. (US) | 2022-03-03 | — | — | WO | disclosed |