Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TTR | P02766 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.50 |
| ▸ | USP2 | O75604 | 1/20 | 0.50 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.50 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.50 |
| ▸ | PTGS2 | P35354 | 4/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.43 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.43 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.43 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.43 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.43 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.43 |
| ▸ | ALB | P02768 | 1/20 | 0.43 |
| ▸ | UGT1A6 | P19224 | 1/20 | 0.43 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.43 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.43 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23158592 | 0.91 | TTR (0.54) | TTRCYP2C9KMT2AUSP2LMNA | |
| SCHEMBL23158632 | 0.88 | TTR (0.50) | TTRCYP2C9KMT2AUSP2LMNA | |
| SCHEMBL23177649 | 0.88 | TTR (0.50) | TTRCYP2C9KMT2AUSP2LMNA | |
| SCHEMBL17001513 | 0.87 | TTR (0.59) | TTRCYP2C9KMT2AUSP2LMNA | |
| SCHEMBL23158577 | 0.86 | CTSS (0.51) | TTRCYP2C9KMT2AUSP2LMNA | |
| SCHEMBL23158797 | 0.84 | TTR (0.46) | TTRCYP2C9KMT2AUSP2LMNA | |
| SCHEMBL23177646 | 0.83 | TTR (0.45) | TTRCYP2C9KMT2AUSP2LMNA | |
| SCHEMBL23158581 | 0.83 | TTR (0.45) | TTRCYP2C9KMT2AUSP2LMNA | |
| SCHEMBL23158657 | 0.83 | TTR (0.41) | TTRCYP2C9KMT2AUSP2LMNA | |
| SCHEMBL23177946 | 0.83 | TTR (0.41) | TTRCYP2C9KMT2AUSP2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021060351-A1 | NSAID-BONDED ALGINIC ACID DERIVATIVE | 持田製薬株式会社 | 2021-04-01 | — | — | WO | disclosed |
| WO-2021060395-A1 | SUSTAINED-RELEASE PHARMACEUTICAL COMPOSITION | 持田製薬株式会社 | 2021-04-01 | — | — | WO | disclosed |