Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDGFRB | P09619 | 8/20 | 0.35 |
| ▸ | KDR | P35968 | 8/20 | 0.35 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 2/20 | 0.30 |
| ▸ | CHEK2 | O96017 | 3/20 | 0.30 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23158867 | 0.90 | PDGFRB (0.39) | PDGFRBKDR | |
| SCHEMBL23158702 | 0.78 | CHEK2 (0.53) | MAP4K4FYNCHEK2CHEK1 | |
| SCHEMBL18861302 | 0.64 | MAPK1 (0.38) | — | |
| SCHEMBL23158688 | 0.64 | AXL (0.51) | MAP4K4FYNCHEK2CHEK1 | |
| SCHEMBL23158685 | 0.61 | CHEK2 (0.53) | MAP4K4FYNCHEK2CHEK1 | |
| SCHEMBL23158795 | 0.61 | — | — | |
| SCHEMBL18860363 | 0.60 | CHEK2 (0.47) | MAP4K4FYNCHEK2CHEK1 | |
| SCHEMBL18860978 | 0.59 | HPGD (0.35) | — | |
| SCHEMBL18861220 | 0.58 | FYN (0.56) | FYNCHEK2CHEK1 | |
| SCHEMBL12518227 | 0.55 | CYP2A6 (0.62) | MAP4K4FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3168219-B1 | PYRIDONE DERIVATIVE HAVING TETRAHYDROPYRANYL METHYL GROUP | DAIICHI SANKYO CO LTD (JP) | 2021-03-31 | — | — | EP | disclosed |