Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 1/20 | 0.38 |
| ▸ | CDK4 | P11802 | 2/20 | 0.37 |
| ▸ | CCND1 | P24385 | 2/20 | 0.37 |
| ▸ | ERCC1 | P07992 | 2/20 | 0.37 |
| ▸ | ERCC4 | Q92889 | 2/20 | 0.37 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.36 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.36 |
| ▸ | BAD | Q92934 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | SERPINE1 | P05121 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.34 |
| ▸ | HPGD | P15428 | 1/20 | 0.34 |
| ▸ | PPARG | P37231 | 1/20 | 0.34 |
| ▸ | RAB9A | P51151 | 1/20 | 0.34 |
| ▸ | PPARD | Q03181 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL14949020 | 0.86 | MAPT (0.36) | NR4A2ERCC1ERCC4SLC6A4SLC6A3 | |
| SCHEMBL28199937 | 0.85 | NR4A2 (0.33) | NR4A2CDK4CCND1ERCC1ERCC4 | |
| SCHEMBL363193 | 0.79 | KDM4E (0.46) | BCL2L1BADSLC6A4SLC6A3KDM4E | |
| SCHEMBL28319846 | 0.77 | SLC6A4 (0.38) | NR4A2BCL2L1BADPTGS1SLC6A4 | |
| SCHEMBL20351754 | 0.75 | BRD4 (0.40) | NR4A2ERCC1ERCC4BCL2L1BAD | |
| SCHEMBL18031340 | 0.75 | NR4A2 (0.40) | NR4A2ERCC1ERCC4GRM2BCL2L1 | |
| SCHEMBL28199967 | 0.75 | GRM2 (0.36) | NR4A2ERCC1ERCC4GRM2BCL2L1 | |
| SCHEMBL17233734 | 0.75 | AURKB (0.42) | ERCC1ERCC4BCL2L1BADPTGS1 | |
| SCHEMBL29757272 | 0.75 | IKBKB (0.43) | GRM2PTGS1SLC6A4SLC6A3AURKB | |
| SCHEMBL10396846 | 0.74 | NR4A2 (0.47) | NR4A2ERCC1ERCC4BCL2L1BAD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3168219-B1 | PYRIDONE DERIVATIVE HAVING TETRAHYDROPYRANYL METHYL GROUP | DAIICHI SANKYO CO LTD (JP) | 2021-03-31 | — | — | EP | disclosed |