Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 10/20 | 0.59 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.55 |
| ▸ | MMEL1 | Q495T6 | 7/20 | 0.53 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.51 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.47 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.45 |
| ▸ | CTSG | P08311 | 1/20 | 0.45 |
| ▸ | CMA1 | P23946 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2315945 | 1.00 | MME (0.59) | MMEFFAR2MMEL1AVPR1AITGB1 | |
| SCHEMBL2317678 | 0.91 | MME (0.60) | MMEFFAR2MMEL1ITGB1ITGA4 | |
| SCHEMBL2317684 | 0.91 | MME (0.60) | MMEFFAR2MMEL1ITGB1ITGA4 | |
| SCHEMBL2319425 | 0.91 | MME (0.52) | MMEFFAR2MMEL1AVPR1AITGB1 | |
| SCHEMBL2319433 | 0.91 | MME (0.52) | MMEFFAR2MMEL1AVPR1AITGB1 | |
| SCHEMBL2312748 | 0.88 | FFAR2 (0.51) | MMEFFAR2MMEL1AVPR1AITGB1 | |
| SCHEMBL2312753 | 0.88 | FFAR2 (0.51) | MMEFFAR2MMEL1AVPR1AITGB1 | |
| SCHEMBL2315652 | 0.87 | MME (0.54) | MMEFFAR2MMEL1AVPR1AITGB1 | |
| SCHEMBL2315641 | 0.87 | MME (0.54) | MMEFFAR2MMEL1AVPR1AITGB1 | |
| SCHEMBL2319527 | 0.86 | FFAR2 (0.65) | MMEFFAR2MMEL1AVPR1AMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092284-A1 | NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS | EUROSCREEN S.A. (BE) | 2011-08-04 | — | — | WO | claimed |