Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADCY1 | Q08828 | 19/20 | 0.74 |
| ▸ | ADCY8 | P40145 | 18/20 | 0.74 |
| ▸ | HTR2B | P41595 | 3/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23160933 | 0.90 | ADCY1 (0.73) | ADCY1ADCY8HTR2B | |
| SCHEMBL23160950 | 0.90 | ADCY1 (0.73) | ADCY1ADCY8HTR2B | |
| SCHEMBL20657977 | 0.89 | ADCY1 (0.72) | ADCY1ADCY8HTR2B | |
| SCHEMBL23160941 | 0.89 | ADCY1 (0.71) | ADCY1ADCY8HTR2B | |
| SCHEMBL20657978 | 0.89 | ADCY1 (0.74) | ADCY1ADCY8HTR2B | |
| SCHEMBL23160931 | 0.87 | ADCY1 (0.76) | ADCY1ADCY8HTR2B | |
| SCHEMBL23160964 | 0.87 | ADCY1 (0.75) | ADCY1ADCY8HTR2B | |
| SCHEMBL23160934 | 0.85 | ADCY1 (0.73) | ADCY1ADCY8HTR2B | |
| SCHEMBL23160930 | 0.85 | ADCY1 (0.71) | ADCY1ADCY8HTR2B | |
| SCHEMBL23188263 | 0.85 | ADCY1 (1.00) | ADCY1ADCY8HTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-12414949-B2 | Pyrazolyl pyrimidinone compounds and the uses thereof | PURDUE RESEARCH FOUNDATION (US) | 2025-09-16 | — | — | US | disclosed |
| US-20230293523-A1 | PYRAZOLYL PYRIMIDINONE COMPOUNDS AND THE USES THEREOF | PURDUE RESEARCH FOUNDATION (US) | 2023-09-21 | — | — | US | disclosed |
| US-20230250084-A1 | PYRAZOLYL PYRIMIDINONE COMPOUNDS AND THE USES THEREOF | PURDUE RESEARCH FOUNDATION (US) | 2023-08-10 | — | — | US | disclosed |
| US-11690844-B2 | Pyrazolyl pyrimidinone compounds and the uses thereof | PURDUE RESEARCH FOUNDATION (US) | 2023-07-04 | — | — | US | disclosed |
| US-20210100797-A1 | PYRAZOLYL PYRIMIDINONE COMPOUNDS AND THE USES THEREOF | PURDUE RESEARCH FOUNDATION (US) | 2021-04-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-12414949-B2 | Pyrazolyl pyrimidinone compounds and the uses thereof | CAP1, ADCY1, ADCYAP1R1 | ADCY1 2/4885ADCY8 9/4885HTR2B 1487/4885 |
| US-11690844-B2 | Pyrazolyl pyrimidinone compounds and the uses thereof | CAP1, ADCY1, ADCYAP1R1 | ADCY1 2/4885ADCY8 9/4885HTR2B 1487/4885 |
| US-20230250084-A1 | PYRAZOLYL PYRIMIDINONE COMPOUNDS AND THE USES THEREOF | CAP1, ADCY1, ADCYAP1R1 | ADCY1 2/4885ADCY8 9/4885HTR2B 1487/4885 |
| US-20230293523-A1 | PYRAZOLYL PYRIMIDINONE COMPOUNDS AND THE USES THEREOF | CAP1, ADCY1, ADCYAP1R1 | ADCY1 2/4885ADCY8 9/4885HTR2B 1487/4885 |
| US-20210100797-A1 | PYRAZOLYL PYRIMIDINONE COMPOUNDS AND THE USES THEREOF | CAP1, ADCY1, ADCYAP1R1 | ADCY1 2/4885ADCY8 9/4885HTR2B 1487/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.