Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR2 | O15552 | 6/20 | 0.71 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.58 |
| ▸ | MME | P08473 | 4/20 | 0.57 |
| ▸ | LMNA | P02545 | 1/20 | 0.50 |
| ▸ | MEN1 | O00255 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.49 |
| ▸ | MMEL1 | Q495T6 | 3/20 | 0.46 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.44 |
| ▸ | CSNK1D | P48730 | 1/20 | 0.44 |
| ▸ | DDR1 | Q08345 | 1/20 | 0.44 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2316158 | 1.00 | FFAR2 (0.71) | FFAR2PIN1MMELMNAMEN1 | |
| SCHEMBL2317635 | 1.00 | FFAR2 (0.71) | FFAR2PIN1MMELMNAMEN1 | |
| SCHEMBL2317644 | 1.00 | FFAR2 (0.71) | FFAR2PIN1MMELMNAMEN1 | |
| SCHEMBL2312580 | 0.91 | FFAR2 (0.72) | FFAR2PIN1MMELMNAMEN1 | |
| SCHEMBL2312583 | 0.91 | FFAR2 (0.72) | FFAR2PIN1MMELMNAMEN1 | |
| SCHEMBL2319384 | 0.89 | FFAR2 (0.80) | FFAR2PIN1MMELMNAMEN1 | |
| SCHEMBL2319383 | 0.89 | FFAR2 (0.80) | FFAR2PIN1MMELMNAMEN1 | |
| SCHEMBL2316618 | 0.88 | FFAR2 (0.82) | FFAR2PIN1MMEMEN1MAPT | |
| SCHEMBL2316614 | 0.88 | FFAR2 (0.82) | FFAR2PIN1MMEMEN1MAPT | |
| SCHEMBL2318899 | 0.88 | FFAR2 (0.82) | FFAR2PIN1MMEMEN1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092284-A1 | NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS | EUROSCREEN S.A. (BE) | 2011-08-04 | — | — | WO | claimed |