SCHEMBL231632

SCHEMBL231632

Clc1ccc(Br)cc1.[MgH2]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
1,4-Dichlorobenzene SCHEMBL10839178 0.96 CYP2A6 (0.61)
SCHEMBL197605 0.96
Water SCHEMBL15842032 0.93
SCHEMBL11575659 0.93
Fluoride SCHEMBL2941684 0.93 CYP2A6 (0.57)
Magnesium SCHEMBL30533117 0.93
Methyl Alcohol SCHEMBL27601464 0.87 CYP2A6 (0.50)
SCHEMBL3869855 0.87 ALDH1A1 (0.55)
SCHEMBL25815230 0.87 ALDH1A1 (0.55)
Chlorobenzene SCHEMBL8942435 0.84 TSHR (0.65)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 426 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119591483-A Synthesis method of (4-chlorophenyl) (4-hydroxy-3, 5-dimethoxy phenyl) methanone 广东莱佛士制药技术有限公司 2025-03-11 CN claimed
CN-118874435-A Preparation method of macroporous adsorption resin for waste gas treatment 蚌埠市天星树脂有限责任公司 2024-11-01 CN claimed
CN-118125969-A Haloperidol with excellent biological performance and preparation method and application thereof 湖南洞庭药业股份有限公司 2024-06-04 CN claimed
CN-117164419-A Chiral synthesis method of bestatin intermediate 江苏联环药业股份有限公司 2023-12-05 CN claimed
CN-113620869-B Preparation method of betrixaban 江西同和药业股份有限公司 2023-04-18 CN claimed
CN-113620869-A Preparation method of betrixaban 江西同和药业股份有限公司 2021-11-09 CN claimed
CN-112538042-A Preparation method of haloperidol 湖南洞庭药业股份有限公司 2021-03-23 CN claimed
EP-2307393-B1 A PROCESS FOR THE PREPARATION OF THE APOPTOSIS PROMOTER ABT-263 ABBOTT LAB (US) 2013-04-10 EP claimed
US-8168784-B2 Processes to make apoptosis promoters ABBOTT LABORATORIES (US) 2012-05-01 US claimed
JP-2011525182-A 2011-09-15 JP claimed
EP-2307393-A1 A PROCESS FOR THE PREPARATION OF THE APOPTOSIS PROMOTER ABT-263 Abbott Laboratories (US) 2011-04-13 EP claimed
US-20090318689-A1 Processes To Make Apoptosis Promoters ABBOTT LABORATORIES (US) 2009-12-24 US claimed
WO-2009155386-A1 A PROCESS FOR THE PREPARATION OF THE APOPTOSIS PROMOTER ABT-263 ABBOTT LABORATORIES (US) 2009-12-23 WO claimed
EP-1064286-A1 SYNTHESIS OF ARYL BORONIC ACIDS BOULDER SCIENTIFIC COMPANY (US) 2001-01-03 EP claimed
WO-1999064428-A1 SYNTHESIS OF ARYL BORONIC ACIDS BOULDER SCIENTIFIC COMPANY (US) 1999-12-16 WO claimed
US-4902833-A Bisphosphine dioxides UNION CARBIDE CHEMICALS AND PLASTICS COMPANY INC. (US) 1990-02-20 US claimed
EP-3994125-B1 MODULATORS OF HSD17B13 AND METHODS OF USE THEREOF REGENERON PHARMA (US) 2025-12-24 EP disclosed
CN-120398677-B Preparation method of mandelic acid derivative 顺毅宜昌化工有限公司 2025-11-11 CN disclosed
US-3947488-A O-Acylation using organothallium compounds TAYLOR EDWARD C 1976-03-30 US disclosed
US-3931302-A ANTIINFLAMMATORY, ANALGESIC ROUSSEL-UCLAF (FR) 1976-01-06 US disclosed