Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NUDT1 | P36639 | 1/20 | 0.39 |
| ▸ | CDK8 | P49336 | 5/20 | 0.37 |
| ▸ | AXL | P30530 | 1/20 | 0.37 |
| ▸ | APP | P05067 | 1/20 | 0.36 |
| ▸ | PIK3CD | O00329 | 2/20 | 0.36 |
| ▸ | PIK3CA | P42336 | 2/20 | 0.36 |
| ▸ | PIK3CB | P42338 | 1/20 | 0.36 |
| ▸ | PIK3CG | P48736 | 1/20 | 0.36 |
| ▸ | RIPK1 | Q13546 | 3/20 | 0.35 |
| ▸ | DYRK1B | Q9Y463 | 2/20 | 0.35 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
| ▸ | BTK | Q06187 | 3/20 | 0.34 |
| ▸ | ITK | Q08881 | 3/20 | 0.34 |
| ▸ | MET | P08581 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | CDK7 | P50613 | 2/20 | 0.33 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.33 |
| ▸ | CCND1 | P24385 | 1/20 | 0.33 |
| ▸ | CCNC | P24863 | 1/20 | 0.33 |
| ▸ | CDK9 | P50750 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23166582 | 0.88 | DYRK1A (0.39) | DYRK1BDYRK1AMET | |
| SCHEMBL23165972 | 0.81 | GSK3B (0.43) | PIK3CDPIK3CGDYRK1BDYRK1AMET | |
| SCHEMBL297772 | 0.78 | CDK8 (0.55) | NUDT1CDK8AXLAPPPIK3CD | |
| SCHEMBL15155057 | 0.71 | JAK2 (0.48) | DYRK1BDYRK1AMETPDGFRBPDGFRA | |
| SCHEMBL7114099 | 0.71 | DYRK1A (0.48) | CDK8DYRK1BDYRK1ABTKITK | |
| SCHEMBL15154912 | 0.71 | SMN1; SMN2 (0.44) | DYRK1BDYRK1AMET | |
| SCHEMBL1365382 | 0.70 | ALDH1A1 (0.51) | NUDT1CDK8AXLPIK3CDPIK3CA | |
| SCHEMBL26630297 | 0.70 | DYRK1A (0.42) | NUDT1CDK8AXLPIK3CDPIK3CA | |
| SCHEMBL7111817 | 0.69 | AXL (0.60) | CDK8AXLRIPK1DYRK1BDYRK1A | |
| SCHEMBL21988117 | 0.69 | TDP1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021067791-A1 | OXALAMIDE COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2021-04-08 | — | — | WO | disclosed |