Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2359853 | 0.93 | BRAF (0.33) | — | |
| SCHEMBL2316981 | 0.92 | SLC6A3 (0.37) | PDE10ASLC6A3 | |
| SCHEMBL2359701 | 0.90 | PDE10A (0.37) | PDE10ASLC6A3 | |
| SCHEMBL2359382 | 0.90 | PSEN1 (0.35) | — | |
| SCHEMBL2359183 | 0.90 | CSNK1D (0.40) | PDE10A | |
| SCHEMBL2319490 | 0.89 | PDE10A (0.36) | PDE10ASLC6A3 | |
| SCHEMBL2318287 | 0.89 | PDE10A (0.34) | PDE10ASLC6A3 | |
| SCHEMBL14719049 | 0.87 | PDE10A (0.34) | PDE10ASLC6A3 | |
| SCHEMBL2358909 | 0.86 | BRAF (0.38) | — | |
| SCHEMBL2359191 | 0.84 | BRAF (0.33) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2528909-A1 | SULFONAMIDO DERIVATIVES OF 3,4-DIARYLPYRAZOLES AS PROTEIN KINASE INHIBITORS | Nerviano Medical Sciences S.r.l. (IT) | 2012-12-05 | — | — | EP | claimed |
| WO-2011092088-A1 | SULFONAMIDO DERIVATIVES OF 3,4-DIARYLPYRAZOLES AS PROTEIN KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2011-08-04 | — | — | WO | claimed |
| EP-2528909-B1 | SULFONAMIDO DERIVATIVES OF 3,4-DIARYLPYRAZOLES AS PROTEIN KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES SRL (IT) | 2016-06-22 | — | — | EP | disclosed |
| WO-2011092088-A1 | SULFONAMIDO DERIVATIVES OF 3,4-DIARYLPYRAZOLES AS PROTEIN KINASE INHIBITORS | NERVIANO MEDICAL SCIENCES S.R.L. (IT) | 2011-08-04 | — | — | WO | disclosed |