Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR4A2 | P43354 | 2/20 | 0.53 |
| ▸ | F7 | P08709 | 1/20 | 0.49 |
| ▸ | F3 | P13726 | 1/20 | 0.49 |
| ▸ | PYGL | P06737 | 1/20 | 0.46 |
| ▸ | NHERF1 | O14745 | 1/20 | 0.44 |
| ▸ | THRA | P10827 | 1/20 | 0.43 |
| ▸ | THRB | P10828 | 1/20 | 0.43 |
| ▸ | GABRP | O00591 | 3/20 | 0.43 |
| ▸ | GABRD | O14764 | 3/20 | 0.43 |
| ▸ | GABRA1 | P14867 | 3/20 | 0.43 |
| ▸ | GABRB1 | P18505 | 3/20 | 0.43 |
| ▸ | GABRG2 | P18507 | 3/20 | 0.43 |
| ▸ | GABRB3 | P28472 | 3/20 | 0.43 |
| ▸ | GABRA5 | P31644 | 3/20 | 0.43 |
| ▸ | GABRA3 | P34903 | 3/20 | 0.43 |
| ▸ | GABRA2 | P47869 | 3/20 | 0.43 |
| ▸ | GABRB2 | P47870 | 3/20 | 0.43 |
| ▸ | GABRA4 | P48169 | 3/20 | 0.43 |
| ▸ | GABRE | P78334 | 3/20 | 0.43 |
| ▸ | GABRA6 | Q16445 | 3/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23207500 | 0.95 | NR4A2 (0.58) | NR4A2F7F3PYGLNHERF1 | |
| SCHEMBL23167610 | 0.91 | F7 (0.58) | NR4A2F7F3NHERF1GABRP | |
| Hydrochloric Acid SCHEMBL23167997 | 0.82 | F7 (0.49) | NR4A2F7F3NHERF1GABRP | |
| SCHEMBL28847710 | 0.80 | F7 (0.61) | NR4A2F7F3PYGLNHERF1 | |
| SCHEMBL23167805 | 0.80 | STING1 (0.39) | NR4A2THRATHRBMTNR1AMTNR1B | |
| SCHEMBL7902669 | 0.78 | MTNR1A (0.57) | NR4A2F7F3PYGLNHERF1 | |
| SCHEMBL24630105 | 0.76 | NR4A2 (0.54) | NR4A2F7F3PYGLNHERF1 | |
| SCHEMBL30386394 | 0.76 | F7 (0.55) | NR4A2F7F3PYGLNHERF1 | |
| SCHEMBL12545431 | 0.75 | NR4A2 (0.52) | NR4A2F7F3NHERF1MTNR1A | |
| SCHEMBL30218664 | 0.74 | NR4A2 (0.52) | NR4A2F7F3PYGLNHERF1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021067805-A1 | OXALAMIDE HETEROBYCYCLIC COMPOUNDS AND COMPOSITIONS FOR TREATING CONDITIONS ASSOCIATED WITH STING ACTIVITY | IFM DUE, INC. (US) | 2021-04-08 | — | — | WO | disclosed |