Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SCD | O00767 | 3/20 | 0.59 |
| ▸ | CHEK2 | O96017 | 14/20 | 0.57 |
| ▸ | MEN1 | O00255 | 1/20 | 0.52 |
| ▸ | THRB | P10828 | 1/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.52 |
| ▸ | ABL1 | P00519 | 1/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2318983 | 0.87 | CHEK2 (0.73) | CHEK2 | |
| SCHEMBL2316764 | 0.87 | CHEK2 (0.77) | SCDCHEK2MEN1THRBKMT2A | |
| SCHEMBL2315701 | 0.86 | SCD (0.56) | SCDCHEK2ABL1 | |
| SCHEMBL2321480 | 0.84 | CHEK2 (0.62) | SCDCHEK2 | |
| SCHEMBL2317165 | 0.84 | SCD (0.59) | SCDCHEK2ABL1 | |
| SCHEMBL2315020 | 0.81 | SCD (0.58) | SCDCHEK2ABL1 | |
| SCHEMBL2315595 | 0.81 | SCD (0.79) | SCDCHEK2ABL1 | |
| SCHEMBL2317056 | 0.80 | SCD (0.79) | SCDCHEK2ABL1 | |
| SCHEMBL2802771 | 0.80 | SIRT2 (0.71) | SCDCHEK2 | |
| SCHEMBL2318114 | 0.79 | SCD (0.80) | SCDCHEK2ABL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2183222-B1 | AZOLORAINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, PHARMACEUTICALS CONTAINING THESE COMPOUNDS, AND THE USE THEREOF | SANOFI SA (FR) | 2011-08-03 | — | — | EP | disclosed |
| EP-2183222-A2 | AZOLORAINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, PHARMACEUTICALS CONTAINING THESE COMPOUNDS, AND THE USE THEREOF | Sanofi-Aventis (FR) | 2010-05-12 | — | — | EP | disclosed |
| WO-2009024287-A2 | AZOLORAINE DERIVATIVES, METHOD FOR THE PRODUCTION THEREOF, PHARMACEUTICALS CONTAINING THESE COMPOUNDS, AND THE USE THEREOF | SANOFI-AVENTIS (FR) | 2009-02-26 | — | — | WO | disclosed |