SCHEMBL2316809

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL3612320	0.83	PDE2A (0.43)	PDE2AGSK3BMC4RSLC6A4CES2
	SCHEMBL2764096	0.83	PDE2A (0.43)	PDE2AGSK3BMC4RSLC6A4CES2
	SCHEMBL6391223	0.80	PDE2A (0.41)	PDE2AALDH1A1GSK3BMC4RSLC6A4
	SCHEMBL9337585	0.79	PDE2A (0.46)	PDE2AALDH1A1GSK3BMC4RCES2
	SCHEMBL3586954	0.78	HSD11B1 (0.46)	PDE2AALDH1A1PSEN1PSEN2APH1B
	SCHEMBL2319191	0.78	PDE2A (0.42)	PDE2AALDH1A1PSEN1PSEN2APH1B
	SCHEMBL2320826	0.78	PDE2A (0.42)	PDE2AALDH1A1PSEN1PSEN2APH1B
	SCHEMBL2319194	0.78	PDE2A (0.42)	PDE2AALDH1A1PSEN1PSEN2APH1B
	SCHEMBL678227	0.76	PDE2A (0.50)	PDE2AALDH1A1GSK3BCES2CES1
	SCHEMBL28161010	0.75	ESR1 (0.48)	ALDH1A1SLC6A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.