SCHEMBL23168533

SCHEMBL23168533

Clc1cccc(-c2ccc3c(c2)Sc2ccccc2O3)c1

nearest known ligand 0.53

Predicted protein targets (top 16)

geneUniProtsupporting neighboursconfidence
ALOX5 P09917 1/20 0.41
TAAR1 Q96RJ0 2/20 0.40
ESR2 Q92731 1/20 0.38
NPC1 O15118 1/20 0.38
TP53 P04637 1/20 0.38
TSHR P16473 1/20 0.38
NFKB1 P19838 1/20 0.38
RAB9A P51151 1/20 0.38
NFKB2 Q00653 1/20 0.38
RELA Q04206 1/20 0.38
SMN1; SMN2 Q16637 1/20 0.38
MAOB P27338 2/20 0.37
ADORA2A P29274 1/20 0.37
ADORA1 P30542 1/20 0.37
PGR P06401 1/20 0.37
MAP4K4 O95819 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL16787350 0.87 CYP1A2 (0.41) ALOX5NPC1RAB9ASMN1; SMN2
SCHEMBL23024872 0.83 AHR (0.48)
SCHEMBL19262250 0.82 AHR (0.34)
SCHEMBL12490399 0.80 PLA2G2A (0.34)
SCHEMBL16863586 0.80 AHR (0.54) ALOX5TAAR1ESR2NPC1TP53
SCHEMBL21305060 0.79 BCHE (0.36) MAP4K4
SCHEMBL12489685 0.78 PLA2G2A (0.35) MAP4K4
SCHEMBL16787291 0.77 CA12 (0.34) ALOX5PGR
SCHEMBL12488555 0.77 PLA2G2A (0.35) MAP4K4
SCHEMBL18961039 0.76 PLA2G2A (0.31)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2021060723-A1 COMPOUND FOR ORGANIC ELECTRONIC ELEMENT, ORGANIC ELECTRONIC ELEMENT COMPRISING SAME, AND ELECTRONIC DEVICE THEREOF 덕산네오룩스 주식회사 2021-04-01 WO disclosed