Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | MME | P08473 | 5/20 | 0.51 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 2/20 | 0.40 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.39 |
| ▸ | NPC1 | O15118 | 1/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.39 |
| ▸ | RAB9A | P51151 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2317033 | 1.00 | MEN1 (0.51) | MEN1KMT2AMMELMNAFFAR2 | |
| SCHEMBL2315478 | 0.85 | MEN1 (0.70) | MEN1KMT2AMMELMNAFFAR2 | |
| SCHEMBL2315472 | 0.85 | MEN1 (0.70) | MEN1KMT2AMMELMNAFFAR2 | |
| SCHEMBL2318159 | 0.84 | MME (0.59) | KMT2AMMEFFAR2 | |
| SCHEMBL2317645 | 0.84 | MME (0.59) | KMT2AMMEFFAR2 | |
| SCHEMBL2317781 | 0.84 | MME (0.47) | KMT2AMMEFFAR2NPC1RAB9A | |
| SCHEMBL2317640 | 0.84 | MME (0.59) | KMT2AMMEFFAR2 | |
| SCHEMBL2317792 | 0.84 | MME (0.47) | KMT2AMMEFFAR2NPC1RAB9A | |
| SCHEMBL2314740 | 0.83 | MEN1 (0.60) | MEN1KMT2AMMELMNAMAPT | |
| SCHEMBL2314735 | 0.83 | MEN1 (0.60) | MEN1KMT2AMMELMNAMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092284-A1 | NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS | EUROSCREEN S.A. (BE) | 2011-08-04 | — | — | WO | claimed |