Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 9/20 | 0.47 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.45 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.45 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.42 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | CNR1 | P21554 | 1/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.41 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.41 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.41 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.41 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2317781 | 1.00 | MME (0.47) | MMEPSMB8PSMB5FFAR2KEAP1 | |
| SCHEMBL2317640 | 0.88 | MME (0.59) | MMEPSMB8PSMB5FFAR2CNR2 | |
| SCHEMBL2317645 | 0.88 | MME (0.59) | MMEPSMB8PSMB5FFAR2CNR2 | |
| SCHEMBL2318159 | 0.88 | MME (0.59) | MMEPSMB8PSMB5FFAR2CNR2 | |
| SCHEMBL2315810 | 0.85 | FFAR2 (0.64) | MMEFFAR2CNR2 | |
| SCHEMBL2315802 | 0.85 | FFAR2 (0.64) | MMEFFAR2CNR2 | |
| SCHEMBL2317023 | 0.84 | MEN1 (0.51) | MMEFFAR2NPC1RAB9AKMT2A | |
| SCHEMBL2317033 | 0.84 | MEN1 (0.51) | MMEFFAR2NPC1RAB9AKMT2A | |
| SCHEMBL2317300 | 0.83 | PSMB8 (0.64) | MMEPSMB8PSMB5FFAR2KEAP1 | |
| SCHEMBL2317301 | 0.83 | PSMB8 (0.64) | MMEPSMB8PSMB5FFAR2KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092284-A1 | NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS | EUROSCREEN S.A. (BE) | 2011-08-04 | — | — | WO | claimed |
| WO-2011092284-A1 | NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS | EUROSCREEN S.A. (BE) | 2011-08-04 | — | — | WO | disclosed |