Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CRBN | Q96SW2 | 17/20 | 0.63 |
| ▸ | DDB1 | Q16531 | 10/20 | 0.58 |
| ▸ | HPGDS | O60760 | 2/20 | 0.49 |
| ▸ | IKZF3 | Q9UKT9 | 2/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.46 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.46 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | TNF | P01375 | 1/20 | 0.45 |
| ▸ | IL1B | P01584 | 1/20 | 0.45 |
| ▸ | TBXA2R | P21731 | 1/20 | 0.45 |
| ▸ | IKZF1 | Q13422 | 1/20 | 0.45 |
| ▸ | EGFR | P00533 | 2/20 | 0.43 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | BTK | Q06187 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL23133938 | 0.86 | CRBN (0.69) | CRBNDDB1HPGDSIKZF3ALDH1A1 | |
| SCHEMBL23133944 | 0.84 | CRBN (0.56) | CRBNDDB1HPGDSEGFR | |
| SCHEMBL25172415 | 0.84 | CRBN (0.80) | CRBNDDB1HPGDSIKZF3ALDH1A1 | |
| SCHEMBL30400867 | 0.84 | CRBN (0.80) | CRBNDDB1HPGDSIKZF3ALDH1A1 | |
| SCHEMBL23117898 | 0.79 | CRBN (0.58) | CRBNDDB1HPGDSEGFRAR | |
| SCHEMBL30139774 | 0.79 | CRBN (0.95) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL21946744 | 0.79 | CRBN (0.95) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL30139721 | 0.79 | CRBN (0.95) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL25170816 | 0.79 | CRBN (1.00) | CRBNDDB1IKZF3ALDH1A1CHRM2 | |
| SCHEMBL30798398 | 0.79 | CRBN (0.95) | CRBNDDB1IKZF3ALDH1A1CHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021061642-A1 | NOVEL UREAS HAVING ANDROGEN RECEPTOR DEGRADATION ACTIVITY AND USES THEREOF | ACCUTAR BIOTECHNOLOGY INC. (US) | 2021-04-01 | — | — | WO | disclosed |