Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.33 |
| ▸ | SMYD3 | Q9H7B4 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
| ▸ | PPARA | Q07869 | 1/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26922502 | 0.80 | MEN1 (0.33) | MAPTSMN1; SMN2ALDH1A1HSD17B10MEN1 | |
| SCHEMBL9285410 | 0.79 | — | — | |
| SCHEMBL3322605 | 0.76 | — | — | |
| SCHEMBL8876022 | 0.75 | PPARA (0.38) | PPARA | |
| SCHEMBL26659533 | 0.75 | NLRP3 (0.35) | SMN1; SMN2PPARA | |
| SCHEMBL15273883 | 0.74 | EPHX2 (0.38) | MAPTTP53THRBHSP90AA1HSP90AB1 | |
| SCHEMBL4861039 | 0.74 | — | — | |
| SCHEMBL12450498 | 0.74 | PPARA (0.45) | TP53SMN1; SMN2PPARAALDH1A1 | |
| SCHEMBL2759543 | 0.74 | — | — | |
| SCHEMBL4469220 | 0.74 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021132524-A1 | EPOXY AZEPAN DERIVATIVE | 日本ケミファ株式会社 | 2021-07-01 | — | — | WO | disclosed |
| WO-2021132524-A1 | EPOXY AZEPAN DERIVATIVE | 日本ケミファ株式会社 | 2021-07-01 | — | — | WO | disclosed |
| WO-2021065898-A1 | AZEPAN DERIVATIVE | 日本ケミファ株式会社 | 2021-04-08 | — | — | WO | disclosed |
| WO-2021065898-A1 | AZEPAN DERIVATIVE | 日本ケミファ株式会社 | 2021-04-08 | — | — | WO | disclosed |