SCHEMBL23175124

SCHEMBL23175124

CCc1ccc2sc(NS)nc2c1CC

nearest known ligand 0.40

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 5/20 0.40
KMT2A Q03164 5/20 0.40
GAA P10253 5/20 0.38
MAPT P10636 4/20 0.38
TDP1 Q9NUW8 2/20 0.38
KDM4E B2RXH2 2/20 0.38
ALDH1A1 P00352 1/20 0.38
PKM P14618 1/20 0.38
MAPK1 P28482 1/20 0.38
NPC1 O15118 5/20 0.36
IDO1 P14902 1/20 0.36
RAB9A P51151 4/20 0.33
SMN1; SMN2 Q16637 3/20 0.33
LMNA P02545 1/20 0.33
POLB P06746 1/20 0.33
DYRK1A Q13627 1/20 0.33
DUSP3 P51452 1/20 0.32
HPGD P15428 1/20 0.32
HTT P42858 1/20 0.32
NPSR1 Q6W5P4 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL22689639 0.82 MEN1 (0.36) MEN1KMT2AGAAMAPTTDP1
SCHEMBL22689594 0.80 NPC1 (0.36) MEN1KMT2AGAAMAPTTDP1
SCHEMBL1771627 0.79 MEN1 (0.31) MEN1KMT2AALDH1A1IDO1
SCHEMBL22981635 0.79 NPC1 (0.36) MEN1KMT2AGAAMAPTTDP1
SCHEMBL22689640 0.77 MAPT (0.36) MEN1KMT2AGAAMAPTTDP1
SCHEMBL23457015 0.77 MAPT (0.36) MEN1KMT2AGAAMAPTTDP1
SCHEMBL22689503 0.77 MAPT (0.36) MEN1KMT2AGAAMAPTTDP1
SCHEMBL23456997 0.77 MAPT (0.36) MEN1KMT2AGAAMAPTTDP1
SCHEMBL22689600 0.77 MAPT (0.36) MEN1KMT2AGAAMAPTTDP1
SCHEMBL22689593 0.77 MAPT (0.36) MEN1KMT2AGAAMAPTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3910107-B1 RUBBER COMPOSITION FOR COATING METAL CORD, STEEL CORD/RUBBER COMPOSITE, TIRE, AND CHEMICAL PRODUCT BRIDGESTONE CORP (JP) 2023-10-25 EP disclosed
EP-3910107-A1 RUBBER COMPOSITION FOR COATING METAL CORD, STEEL CORD/RUBBER COMPOSITE, TIRE, AND CHEMICAL PRODUCT BRIDGESTONE CORPORATION (JP) 2021-11-17 EP disclosed
US-20210171744-A1 TIRE RUBBER COMPOSITION AND TIRE BRIDGESTONE CORPORATION (JP) 2021-06-10 US disclosed
WO-2021066106-A1 RUBBER COMPOSITION AND RUN-FLAT TIRE 株式会社ブリヂストン 2021-04-08 WO disclosed
WO-2021066099-A1 RUN-FLAT TIRE 株式会社ブリヂストン 2021-04-08 WO disclosed