Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.36 |
| ▸ | TYR | P14679 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | BCHE | P06276 | 2/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL22689503 | 1.00 | MAPT (0.36) | MAPTTYRMEN1KMT2ATDP1 | |
| SCHEMBL23456997 | 1.00 | MAPT (0.36) | MAPTTYRMEN1KMT2ATDP1 | |
| SCHEMBL22689600 | 1.00 | MAPT (0.36) | MAPTTYRMEN1KMT2ATDP1 | |
| SCHEMBL22689640 | 1.00 | MAPT (0.36) | MAPTTYRMEN1KMT2ATDP1 | |
| SCHEMBL23457015 | 1.00 | MAPT (0.36) | MAPTTYRMEN1KMT2ATDP1 | |
| SCHEMBL22981635 | 0.99 | NPC1 (0.36) | MAPTTYRMEN1KMT2ATDP1 | |
| SCHEMBL22689594 | 0.95 | NPC1 (0.36) | MAPTTYRMEN1KMT2ATDP1 | |
| SCHEMBL22689639 | 0.86 | MEN1 (0.36) | MAPTMEN1KMT2ATDP1NPC1 | |
| SCHEMBL23175124 | 0.77 | MEN1 (0.40) | MAPTMEN1KMT2ATDP1HTT | |
| SCHEMBL4539621 | 0.76 | TYR (0.36) | MAPTTYRMEN1KMT2ATDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2021066099-A1 | RUN-FLAT TIRE | 株式会社ブリヂストン | 2021-04-08 | — | — | WO | disclosed |
| WO-2021066106-A1 | RUBBER COMPOSITION AND RUN-FLAT TIRE | 株式会社ブリヂストン | 2021-04-08 | — | — | WO | disclosed |
| WO-2020235230-A1 | RUBBER COMPOSITION, RUBBER COMPOSITION FOR TIRE, AND TIRE | 株式会社ブリヂストン (JP) | 2020-11-26 | — | — | WO | disclosed |