Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.57 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.57 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.57 |
| ▸ | LMNA | P02545 | 2/20 | 0.57 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.57 |
| ▸ | HPGD | P15428 | 2/20 | 0.57 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.57 |
| ▸ | TP53 | P04637 | 1/20 | 0.57 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.57 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.57 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.57 |
| ▸ | GMNN | O75496 | 1/20 | 0.57 |
| ▸ | APEX1 | P27695 | 1/20 | 0.57 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.57 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.42 |
| ▸ | HTT | P42858 | 9/20 | 0.41 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Propaquizafop SCHEMBL54333 | 0.96 | MAPT (0.61) | ALDH1A1CYP1A2MAPTCYP3A4LMNA | |
| Propaquizafop SCHEMBL9136963 | 0.96 | MAPT (0.61) | ALDH1A1CYP1A2MAPTCYP3A4LMNA | |
| Propaquizafop SCHEMBL43925 | 0.96 | MAPT (0.61) | ALDH1A1CYP1A2MAPTCYP3A4LMNA | |
| Propaquizafop SCHEMBL8540160 | 0.92 | MAPT (0.58) | ALDH1A1CYP1A2MAPTCYP3A4LMNA | |
| Propaquizafop SCHEMBL28841958 | 0.90 | MAPT (0.56) | ALDH1A1CYP1A2MAPTCYP3A4LMNA | |
| SCHEMBL10959202 | 0.89 | MAPT (0.63) | ALDH1A1CYP1A2MAPTCYP3A4LMNA | |
| Propaquizafop SCHEMBL28163652 | 0.87 | MAPT (0.52) | ALDH1A1CYP1A2MAPTCYP3A4LMNA | |
| Propaquizafop SCHEMBL9739797 | 0.87 | MAPT (0.49) | ALDH1A1CYP1A2MAPTCYP3A4LMNA | |
| Propaquizafop SCHEMBL28163665 | 0.87 | MAPT (0.49) | ALDH1A1CYP1A2MAPTCYP3A4LMNA | |
| SCHEMBL10732452 | 0.87 | ALDH1A1 (0.46) | ALDH1A1CYP1A2MAPTCYP3A4LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011094219-A1 | VESICULAR FORMULATIONS | KROON HENDRICK-ANDRE (US) | 2011-08-04 | — | — | WO | disclosed |