Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 7/20 | 0.53 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.53 |
| ▸ | PIN1 | Q13526 | 3/20 | 0.52 |
| ▸ | PSMB8 | P28062 | 1/20 | 0.51 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.51 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.50 |
| ▸ | MAPK8 | P45983 | 1/20 | 0.48 |
| ▸ | GSK3A | P49840 | 1/20 | 0.48 |
| ▸ | MAPK10 | P53779 | 1/20 | 0.48 |
| ▸ | HIPK1 | Q86Z02 | 1/20 | 0.48 |
| ▸ | RIOK2 | Q9BVS4 | 1/20 | 0.48 |
| ▸ | SNRK | Q9NRH2 | 1/20 | 0.48 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.47 |
| ▸ | NFE2L2 | Q16236 | 2/20 | 0.47 |
| ▸ | CNR1 | P21554 | 1/20 | 0.47 |
| ▸ | CNR2 | P34972 | 1/20 | 0.47 |
| ▸ | MMEL1 | Q495T6 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2317585 | 1.00 | MME (0.53) | MMEFFAR2PIN1PSMB8PSMB5 | |
| SCHEMBL2320218 | 0.95 | PIN1 (0.55) | MMEFFAR2PIN1PSMB8PSMB5 | |
| SCHEMBL2320209 | 0.95 | PIN1 (0.55) | MMEFFAR2PIN1PSMB8PSMB5 | |
| SCHEMBL2315766 | 0.90 | MME (0.55) | MMEFFAR2PIN1NR1H4MAPK8 | |
| SCHEMBL2317412 | 0.90 | MME (0.55) | MMEFFAR2PIN1NR1H4MAPK8 | |
| SCHEMBL2315763 | 0.90 | MME (0.55) | MMEFFAR2PIN1NR1H4MAPK8 | |
| SCHEMBL2312829 | 0.89 | PIN1 (0.54) | MMEFFAR2PIN1NR1H4MAPK8 | |
| SCHEMBL2312838 | 0.89 | PIN1 (0.54) | MMEFFAR2PIN1NR1H4MAPK8 | |
| SCHEMBL2317301 | 0.89 | PSMB8 (0.64) | MMEFFAR2PSMB8PSMB5KEAP1 | |
| SCHEMBL2317300 | 0.89 | PSMB8 (0.64) | MMEFFAR2PSMB8PSMB5KEAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092284-A1 | NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS | EUROSCREEN S.A. (BE) | 2011-08-04 | — | — | WO | claimed |