Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB2 | P05107 | 19/20 | 0.56 |
| ▸ | ICAM1 | P05362 | 19/20 | 0.56 |
| ▸ | ITGAL | P20701 | 19/20 | 0.56 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.46 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13894109 | 0.91 | ITGB2 (0.57) | ITGB2ICAM1ITGAL | |
| SCHEMBL18867795 | 0.88 | ITGB2 (0.69) | ITGB2ICAM1ITGALHDAC6CYP2C9 | |
| SCHEMBL12500613 | 0.81 | ITGB2 (0.55) | ITGB2ICAM1ITGAL | |
| SCHEMBL12063527 | 0.81 | ITGB2 (0.57) | ITGB2ICAM1ITGAL | |
| SCHEMBL16270928 | 0.80 | ITGB2 (0.57) | ITGB2ICAM1ITGAL | |
| SCHEMBL22296809 | 0.80 | ITGB2 (0.57) | ITGB2ICAM1ITGAL | |
| SCHEMBL23153576 | 0.80 | ITGB2 (0.57) | ITGB2ICAM1ITGAL | |
| SCHEMBL19158602 | 0.80 | ITGB2 (0.57) | ITGB2ICAM1ITGAL | |
| SCHEMBL25912577 | 0.79 | ITGB2 (0.56) | ITGB2ICAM1ITGAL | |
| SCHEMBL17992459 | 0.79 | ITGB2 (0.55) | ITGB2ICAM1ITGAL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3797775-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF DIABETIC RETINOPATHY | Novartis AG (CH) | 2021-03-31 | — | — | EP | disclosed |