Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 6/20 | 0.50 |
| ▸ | PSMB5 | P28074 | 5/20 | 0.47 |
| ▸ | PSMB8 | P28062 | 4/20 | 0.47 |
| ▸ | FFAR2 | O15552 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 1/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.42 |
| ▸ | CTSB | P07858 | 2/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.40 |
| ▸ | CTSS | P25774 | 1/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.40 |
| ▸ | MAOB | P27338 | 1/20 | 0.40 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2317672 | 1.00 | MME (0.50) | MMEPSMB5PSMB8FFAR2MEN1 | |
| SCHEMBL2314826 | 0.86 | MME (0.49) | MMEPSMB5PSMB8PIN1MAOB | |
| SCHEMBL2314822 | 0.86 | MME (0.49) | MMEPSMB5PSMB8PIN1MAOB | |
| SCHEMBL2314809 | 0.83 | MME (0.53) | MMEPSMB5PSMB8FFAR2CTSB | |
| SCHEMBL2314812 | 0.83 | MME (0.53) | MMEPSMB5PSMB8FFAR2CTSB | |
| SCHEMBL2311982 | 0.79 | PSMB8 (0.54) | MMEPSMB5PSMB8FFAR2MEN1 | |
| SCHEMBL2311985 | 0.79 | PSMB8 (0.54) | MMEPSMB5PSMB8FFAR2MEN1 | |
| SCHEMBL2316203 | 0.79 | MME (0.52) | MMEPSMB5PSMB8FFAR2MEN1 | |
| SCHEMBL2316192 | 0.79 | MME (0.52) | MMEPSMB5PSMB8FFAR2MEN1 | |
| SCHEMBL2317942 | 0.77 | MME (0.56) | MMEPSMB5PSMB8FFAR2MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092284-A1 | NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS | EUROSCREEN S.A. (BE) | 2011-08-04 | — | — | WO | claimed |