Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 3/20 | 0.49 |
| ▸ | PSMB5 | P28074 | 5/20 | 0.48 |
| ▸ | PSMB8 | P28062 | 3/20 | 0.44 |
| ▸ | CTSA | P10619 | 1/20 | 0.40 |
| ▸ | PIN1 | Q13526 | 1/20 | 0.39 |
| ▸ | MAOB | P27338 | 1/20 | 0.39 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.38 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.38 |
| ▸ | AKR1B1 | P15121 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2314826 | 1.00 | MME (0.49) | MMEPSMB5PSMB8CTSAPIN1 | |
| SCHEMBL2317672 | 0.86 | MME (0.50) | MMEPSMB5PSMB8PIN1MAOB | |
| SCHEMBL2317677 | 0.86 | MME (0.50) | MMEPSMB5PSMB8PIN1MAOB | |
| SCHEMBL2313800 | 0.83 | MME (0.47) | MMEPSMB5PSMB8PIN1 | |
| SCHEMBL2313795 | 0.83 | MME (0.47) | MMEPSMB5PSMB8PIN1 | |
| SCHEMBL2318812 | 0.82 | MME (0.44) | MMEPSMB5PSMB8 | |
| SCHEMBL2318821 | 0.82 | MME (0.44) | MMEPSMB5PSMB8 | |
| SCHEMBL13702567 | 0.78 | MME (0.53) | MMEPSMB5PSMB8PIN1FFAR1 | |
| SCHEMBL13702569 | 0.78 | MME (0.53) | MMEPSMB5PSMB8PIN1FFAR1 | |
| SCHEMBL2313611 | 0.78 | MME (0.58) | MMEPSMB5PSMB8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011092284-A1 | NOVEL AMINO ACID DERIVATIVES AND THEIR USE AS GPR43 RECEPTOR MODULATORS | EUROSCREEN S.A. (BE) | 2011-08-04 | — | — | WO | claimed |