SCHEMBL23178148

SCHEMBL23178148

NC(=O)C(Cc1c[nH]c2ccccc12)NC(=O)C(N)Cc1ccc(N)cc1

nearest known ligand 0.60

Predicted protein targets (top 4)

geneUniProtsupporting neighboursconfidence
ECE1 P42892 2/20 0.60
NPY1R P25929 2/20 0.56
NPY2R P49146 2/20 0.56
NPY4R P50391 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL29440410 1.00 ECE1 (0.60) ECE1NPY1RNPY2RNPY4R
SCHEMBL30799684 0.92 ECE1 (0.64) ECE1
SCHEMBL22133113 0.92 ECE1 (0.64) ECE1
SCHEMBL13725698 0.92 ECE1 (0.64) ECE1
SCHEMBL23178151 0.92 ERAP1 (0.64) ECE1
SCHEMBL30291268 0.90 ECE1 (0.69) ECE1NPY1RNPY2RNPY4R
SCHEMBL5558360 0.90 ECE1 (0.69) ECE1NPY1RNPY2RNPY4R
SCHEMBL31722484 0.88 KDM4E (0.62) ECE1
Hydrochloric Acid SCHEMBL8982603 0.87 KDM4E (0.60) ECE1
SCHEMBL6466771 0.87

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-3500252-B1 MODIFIED PEPTIDES FOR USE IN TREATING NEURODEGENERATIVE DISORDERS NEURO BIO LTD (GB) 2022-11-02 EP disclosed
US-20210094983-A1 MODIFIED PEPTIDES FOR USE IN TREATING NEURODEGENERATIVE DISORDERS NEURO-BIO LTD. (GB) 2021-04-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210094983-A1 MODIFIED PEPTIDES FOR USE IN TREATING NEURODEGENERATIVE DISORDERS IAPP, NLN, APP ECE1 774/4885NPY1R 180/4885NPY2R 266/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.